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Search Results for " 3c-like "

14

Compounds

Cat No. Product Name Synonyms Targets
T14968 Cinanserin hydrochloride SQ 10643 Influenza Virus , 5-HT Receptor
Cinanserin hydrochloride (SQ 10643) is a high affinity antagonist of the 5-HT2 receptor (Ki: 41 nM) and a 3C-like protease inhibitor of severe acute respiratory syndrome coronavirus.
T5188 GC376 sodium SARS-CoV
GC376 is an inhibitor of 3C-like proteases (3CLpro) with IC50 values range from 0.49~4.35 μM.
T9458 PF-00835231 SARS-CoV
PF-00835231 is a CoV-2 cysteine 3C-like protease (3CLpro) inhibitor, with IC50s of 0.27 nM and 4 nM for SARS CoV-2 and SARS CoV-1 3CLpro, respectively.PF-00835231 is the active compound of the first anti-3CLpro regimen i...
T9351 Nirmatrelvir SARS-CoV
PF-07321332 is a potent and orally active inhibitor of SARS-CoV 3C-like protease (3CLPRO) .
T70564 NPI64
NPI64 is a broad-spectrum coronavirus protease inhibitor which inhibits viral 3C and 3C-like protease.
T71817 CID-948801
CID-948801 is a novel 3C-like protease inhibitor of SARS-CoV-2.
T68674 Vincapusine
Vincapusine is a natural inhibitor of 3C-like protease (3CLpro), targeting SARS-CoV-2 3CLpro, SARS-CoV 3CLpro and MERS-CoV 3CLpro.
T60962 SARS-CoV-2-IN-18
SARS-CoV-2-IN-18 (Compound 26) is a potent inhibitor of SARS-CoV-2 3C-like protease (IC50 = 45 nM) [1].
T72671 SARS-CoV-2-IN-12
SARS-CoV-2-IN-12, a potent inhibitor of the SARS-CoV-2-related 3C-like protease (K_i=32.1 pM), plays a crucial role in preventing SARS-CoV-2 viral replication, showcasing potential significance in COVID-19 research.
T40341 SARS-CoV-2-IN-11
SARS-CoV-2-IN-11 is a highly potent and non-toxic inhibitor of the 3C-like protease (3CLpro) of SARS-CoV-2, demonstrating IC50 and EC50 values of 0.17 nM and 1.45 nM, respectively. This compound targets the essential vir...
T72364 SARS-CoV-2 3CLpro-IN-5 SARS-CoV
SARS-CoV-2 3CLpro-IN-5 is a covalent inhibitor targeting the 3C-like protease (3CLpro), exhibiting potent inhibitory activity with an IC50 of 3.8 nM and demonstrating 9.0% oral bioavailability (BA). It is utilized in the...
T40340 SARS-CoV-2-IN-10
SARS-CoV-2-IN-10 is a powerful and non-toxic inhibitor of SARS-CoV-2 3CL protease, with IC50 and EC50 values of 0.13 nM and 1.03 nM, respectively. The SARS-CoV-2 3C-like protease (3CLpro) is a critical enzyme for viral r...
T79866 Zevotrelvir SARS-CoV
Zevotrelvir (Compound 52) serves as an inhibitor of coronavirus, demonstrating IC50 values below 0.1 μM for 229E hCoV protease and below 0.1 mM for SARS-CoV-3C-like (3CL) protease, suggesting its potential for researchin...
T83719 Mca-AVLQSGFR-K(Dnp)-K-NH2 TFA
Mca-AVLQSGFR-K(Dnp)-K-NH2 serves as a fluorogenic substrate specifically designed for the main protease (Mpro) of the severe acute respiratory syndrome coronavirus (SARS-CoV), also referred to as 3C-like protease (3CLpro...
TargetMol