3
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T4211 | SAG hydrochloride (912545-86-9(free base)) | Smoothened Agonist HCl | Hedgehog/Smoothened |
SAG hydrochloride (912545-86-9(free base)) (Smoothened Agonist HCl) acts as an SMO agonist. | |||
T40465 | SAG dihydrochloride | Hedgehog/Smoothened | |
SAG dihydrochloride, a powerful agonist of the Smoothened (Smo) receptor (EC 50 = 3 nM; Kd = 59 nM), effectively activates the Hedgehog signaling pathway. It also negates the effects of Cyclopamine inhibition on Smo. | |||
T1779 | SAG | Smoothened Agonist (SAG) HCl,Smoothened Agonist | Hedgehog/Smoothened , Smo |
SAG (Smoothened Agonist) is a Smo receptor agonist (EC50=3 nM) that is cell-permeable and selective. SAG regulates Smo activity by binding directly to the Smo helix and can activate the Hedgehog signaling pathway. |