4
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T15038 | Momelotinib sulfate | CYT387 sulfate salt | JAK |
Momelotinib sulfate is an ATP-competitive JAK1/JAK2 inhibitor (IC50: 11 nM/18 nM). It has 10-fold selectivity versus JAK3. | |||
T15037 | Momelotinib Mesylate | CYT387 (Mesylate) | JAK |
Momelotinib Mesylate is an ATP-competitive JAK1/JAK2 inhibitor (IC50: 11 nM/18 nM). It has 10-fold selectivity versus JAK3. | |||
T70823 | Momelotinib HCl | ||
Momelotinib HCl is a JAK1/2 inhibitor, reducing anemia in myelofibrosis (MF) patients. | |||
T1849 | Momelotinib | CYT11387,CYT387,LM-1149 | Apoptosis , JAK , Autophagy |
Momelotinib (LM-1149) is an orally bioavailable small-molecule inhibitor of Janus kinases 1 and 2 (JAK1/2) with IC50 of 11 nM/18 nM. JAK1/2 inhibitor CYT387 competes with JAK1/2 for ATP binding, which may result in inhib... |