Platelets are a component of blood whose function (along with the coagulation factors) is to react to bleeding from blood vessel injury by clumping, thereby initiating a blood clot. Platelets have no cell nucleus; they are fragments of cytoplasm derived from the megakaryocytes of the bone marrow or lung, which then enter the circulation. Platelets are found only in mammals, whereas in other vertebrates, thrombocytes circulate as intact mononuclear cells. Quiescent platelets express a large number of surface proteins, including CD9, CD29, CD31, CD36, CD41, CD42a, CD42b, CD61 and gpvi2,3. Some molecules, such as CD41 and CD61, increase their surface levels after platelet activation, while other proteins that are virtually absent on the surface of quiescent platelets, such as CD62P, CD63, CD107a, and CD154, are transferred from intracellular storage to the plasma membrane after activation.
Cat No. | product name / Synonyms | Species | Expression System |
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TMPK-00422 | PDGF R beta/CD140b Protein, Human, Recombinant (His & Avi), Biotinylated
PDGF R beta/CD140b Protein, Human, Recombinant (His & Avi), Biotinylated
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Human | HEK293 Cells |
PDGF R beta/CD140b Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weigh... | |||
TMPK-00481 | PDGF R beta/CD140b Protein, Cynomolgus, Recombinant (His)
PDGF R beta/CD140b Protein, Cynomolgus, Recombinant (His)
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Cynomolgus | HEK293 Cells |
Platelet-derived growth factor receptor (PDGFR) signaling is involved in proliferation and survival in a wide array of cell types.PDGFR-β signalling, via TGF-β s... | |||
TMPK-00494 | C-MPL Protein, Cynomolgus, Recombinant (His)
C-MPL Protein, Cynomolgus, Recombinant (His)
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Cynomolgus | HEK293 Cells |
C-MPL Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 53.48 kDa and the accession... | |||
TMPK-00497 | ICAM-1/CD54 Protein, Cynomolgus, Recombinant (His)
ICAM-1/CD54 Protein, Cynomolgus, Recombinant (His)
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Cynomolgus | HEK293 Cells |
Intercellular adhesion molecule-1 (ICAM-1; CD54) is a 90 kDa member of the immunoglobulin (Ig) superfamily and is critical for the firm arrest and transmigration... | |||
TMPK-00509 | E-Cadherin/Cadherin-1 Protein, Cynomolgus, Recombinant (His)
E-Cadherin/Cadherin-1 Protein, Cynomolgus, Recombinant (His)
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Cynomolgus | HEK293 Cells |
E-cadherin is the core component of epithelial adherens junctions, essential for tissue development, differentiation, and maintenance. It is also fundamental for... | |||
TMPK-00532 | CD46 Protein, Cynomolgus, Recombinant (His)
CD46 Protein, Cynomolgus, Recombinant (His)
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Cynomolgus | HEK293 Cells |
CD46 was discovered in 1986 during a search for novel C3b-binding proteins. CD46 is expressed ubiquitously and functions as a co-factor in the factor I-mediated ... | |||
TMPK-00550 | CD55/DAF Protein, Cynomolgus, Recombinant (His)
CD55/DAF Protein, Cynomolgus, Recombinant (His)
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Cynomolgus | HEK293 Cells |
Decay Accelerating Factor (or CD55) is a major regulator of the alternative and classical pathways of complement activation and is expressed on all serum-exposed... | |||
TMPK-00570 | CD46 Protein, Canine, Recombinant (His)
CD46 Protein, Canine, Recombinant (His)
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Canine | HEK293 Cells |
CD46 was discovered in 1986 during a search for novel C3b-binding proteins. CD46 is expressed ubiquitously and functions as a co-factor in the factor I-mediated ... | |||
TMPK-00587 | CDH11 Protein, Human, Recombinant (aa 54-617, His)
CDH11 Protein, Human, Recombinant (aa 54-617, His)
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Human | HEK293 Cells |
CDH11 belongs to a group of transmembrane proteins that are principally located in adherens junctions. CDH11 mediates homophilic cell-to-cell adhesion, which may... | |||
TMPK-00644 | CD47 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)
CD47 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)
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Cynomolgus,Rhesus | HEK293 Cells |
CD47 (Cluster of Differentiation 47) also known as integrin associated protein (IAP) is a transmembrane protein that in humans is encoded by the CD47 gene. CD47 ... | |||
TMPK-00819 | CD42a/GP9 Protein, Human, Recombinant (hFc)
CD42a/GP9 Protein, Human, Recombinant (hFc)
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Human | HEK293 Cells |
Filamentous M13 phage extrude from infected Escherichia coli with a tip structure composed of gp7 and gp9. This tip structure is extended by the assembly of the ... | |||
TMPK-00827 | CD43 Protein, Mouse, Recombinant (His)
CD43 Protein, Mouse, Recombinant (His)
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Mouse | HEK293 Cells |
CD43 is a large transmembrane protein involved in T cell activation. Previous studies of CD43-/- mice in viral models have demonstrated a role for CD43 in Th1/Th... | |||
TMPK-00830 | P-Selectin Protein, Human, Recombinant (Avi & His), Biotinylated
P-Selectin Protein, Human, Recombinant (Avi & His), Biotinylated
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Human | HEK293 Cells |
Human P-Selectin (GMP-140, LECAM-3, PADGEM, CD62P), a member of the Selectin family, is a cell surface glycoprotein expressed by activated platelets and endothel... | |||
TMPK-00832 | CD43 Protein, Human, Recombinant (His)
CD43 Protein, Human, Recombinant (His)
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Human | HEK293 Cells |
CD43 (leukosialin) is a large sialoglycoprotein abundantly expressed on the surface of most cells from the hematopoietic lineage. CD43 is directly involved in th... | |||
TMPK-00872 | ICAM-1/CD54 Protein, Canine, Recombinant (His)
ICAM-1/CD54 Protein, Canine, Recombinant (His)
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Canine | HEK293 Cells |
Intercellular adhesion molecule-1 (ICAM-1; CD54) is a 90 kDa member of the immunoglobulin (Ig) superfamily and is critical for the firm arrest and transmigration... | |||
TMPK-00876 | G-CSFR/CD114 Protein, Mouse, Recombinant (His)
G-CSFR/CD114 Protein, Mouse, Recombinant (His)
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Mouse | HEK293 Cells |
The Granulocyte Colony-Stimulating Factor (G-CSF) receptor, a member of the hematopoietin cytokine receptor superfamily, functions as a homodimer and requires th... | |||
TMPK-00877 | C-MPL Protein, Human, Recombinant (aa 26-491, His)
C-MPL Protein, Human, Recombinant (aa 26-491, His)
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Human | HEK293 Cells |
C-MPL Protein, Human, Recombinant (aa 26-491, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 53.6 kDa and the acce... | |||
TMPK-00903 | GP1BB Protein, Mouse, Recombinant (hFc)
GP1BB Protein, Mouse, Recombinant (hFc)
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Mouse | HEK293 Cells |
GP1BB Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 39.5 kDa and the accession numbe... | |||
TMPK-00940 | C-MPL Protein, Mouse, Recombinant (aa 26-482, His)
C-MPL Protein, Mouse, Recombinant (aa 26-482, His)
|
Mouse | HEK293 Cells |
C-MPL Protein, Mouse, Recombinant (aa 26-482, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 52.3 kDa and the acce... | |||
TMPK-00943 | PDGF R alpha/PDGFRA Protein, Cynomolgus, Recombinant (His)
PDGF R alpha/PDGFRA Protein, Cynomolgus, Recombinant (His)
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Cynomolgus | HEK293 Cells |
Platelet-derived growth factor is commonly known as a mitogen. Many research data suggest a role for PDGF-beta R in the mitogenic response of mesangial cells. Th... |