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Platelet-Derived Growth Factor Receptors, PDGFRs

Platelet-derived growth factor receptors (PDGF-R) are cell surface tyrosine kinase receptors for members of the platelet-derived growth factor (PDGF) family. PDGF subunits -A and -B are important factors regulating cell proliferation, cellular differentiation, cell growth, development and many diseases including cancer. There are two forms of the PDGF-R, alpha and beta each encoded by a different gene. Depending on which growth factor is bound, PDGF-R homo- or heterodimerizes. Examination of the different signaling cascades induced by RTKs established Ras/MAPK, PI3K, and phospholipase-γ (PLCγ) pathways as key downstream mediators of PDGFR signaling. In addition, reactive oxygen species (ROS)-dependent STAT3 activation has been established to be a key downstream mediator of PDGFR signaling in vascular smooth muscle cells.

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Species
Canine (1)
Cynomolgus (3)
Human (11)
Mouse (2)
Rat (4)
Rhesus (2)
Expression System
HEK293 Cells (23)
Tag
Avi (1)
C-C-His (1)
C-His (6)
C-His-Avi (4)
C-hFc (5)
His (5)
Tag Free (1)
hFc (1)
Cat No. product name / Synonyms Species Expression System
TMPK-00419 PDGF R alpha/PDGFRA Protein, Human, Recombinant (His & Avi)
PDGF R alpha/PDGFRA Protein, Human, Recombinant (His & Avi)
Human HEK293 Cells
Platelet-derived growth factor is commonly known as a mitogen. Many research data suggest a role for PDGF-beta R in the mitogenic response of mesangial cells. Th...
TMPK-00420 PDGF R alpha/PDGFRA Protein, Human, Recombinant (His & Avi), Biotinylated
PDGF R alpha/PDGFRA Protein, Human, Recombinant (His & Avi), Biotinylated
Human HEK293 Cells
Platelet-derived growth factor is commonly known as a mitogen. Many research data suggest a role for PDGF-beta R in the mitogenic response of mesangial cells. Th...
TMPK-00421 PDGF R beta/CD140b Protein, Human, Recombinant (His & Avi)
PDGF R beta/CD140b Protein, Human, Recombinant (His & Avi)
Human HEK293 Cells
PDGF R beta/CD140b Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 59 kDa an...
TMPK-00422 PDGF R beta/CD140b Protein, Human, Recombinant (His & Avi), Biotinylated
PDGF R beta/CD140b Protein, Human, Recombinant (His & Avi), Biotinylated
Human HEK293 Cells
PDGF R beta/CD140b Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weigh...
TMPK-00481 PDGF R beta/CD140b Protein, Cynomolgus, Recombinant (His)
PDGF R beta/CD140b Protein, Cynomolgus, Recombinant (His)
Cynomolgus HEK293 Cells
Platelet-derived growth factor receptor (PDGFR) signaling is involved in proliferation and survival in a wide array of cell types.PDGFR-β signalling, via TGF-β s...
TMPK-00943 PDGF R alpha/PDGFRA Protein, Cynomolgus, Recombinant (His)
PDGF R alpha/PDGFRA Protein, Cynomolgus, Recombinant (His)
Cynomolgus HEK293 Cells
Platelet-derived growth factor is commonly known as a mitogen. Many research data suggest a role for PDGF-beta R in the mitogenic response of mesangial cells. Th...
TMPK-01050 PDGF R beta/CD140b Protein, Canine, Recombinant (His)
PDGF R beta/CD140b Protein, Canine, Recombinant (His)
Canine HEK293 Cells
PDGF R beta/CD140b Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 57.25 kDa and the ...
TMPY-00385 PDGFRB Protein, Rhesus, Recombinant (hFc)
PDGFRB Protein, Rhesus, Recombinant (hFc)
Rhesus HEK293 Cells
PDGFRB Protein, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 83.3 kDa and the accession numbe...
TMPY-00900 PDGFRA Protein, Human, Recombinant (hFc)
PDGFRA Protein, Human, Recombinant (hFc)
Human HEK293 Cells
PDGFRA Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 82.9 kDa and the accession number...
TMPY-01207 PDGFRB Protein, Human, Recombinant (His)
PDGFRB Protein, Human, Recombinant (His)
Human HEK293 Cells
PDGFRB Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.6 kDa and the accession number...
TMPY-03140 PDGFRB Protein, Rat, Recombinant (His)
PDGFRB Protein, Rat, Recombinant (His)
Rat HEK293 Cells
PDGFRB Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.6 kDa and the accession number i...
TMPY-03474 PDGFRB Protein, Rat, Recombinant (hFc)
PDGFRB Protein, Rat, Recombinant (hFc)
Rat HEK293 Cells
PDGFRB Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 83.2 kDa and the accession number i...
TMPY-03590 PDGFRB Protein, Rhesus, Recombinant (His)
PDGFRB Protein, Rhesus, Recombinant (His)
Rhesus HEK293 Cells
PDGFRB Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.7 kDa and the accession numbe...
TMPY-03825 PDGFRA Protein, Rat, Recombinant (His)
PDGFRA Protein, Rat, Recombinant (His)
Rat HEK293 Cells
PDGFRA Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.6 kDa and the accession number i...
TMPY-03919 PDGFRA Protein, Rat, Recombinant (hFc)
PDGFRA Protein, Rat, Recombinant (hFc)
Rat HEK293 Cells
PDGFRA Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 83.2 kDa and the accession number i...
TMPY-04937 PDGFRB Protein, Human, Recombinant (His), Biotinylated
PDGFRB Protein, Human, Recombinant (His), Biotinylated
Human HEK293 Cells
PDGFRB Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.6 kDa and the ac...
TMPY-05358 PDGFRB Protein, Human, Recombinant
PDGFRB Protein, Human, Recombinant
Human HEK293 Cells
PDGFRB Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 56.2 kDa and the accession number is P09619-1.
TMPY-05497 PDGFRB Protein, Human, Recombinant (hFc)
PDGFRB Protein, Human, Recombinant (hFc)
Human HEK293 Cells
PDGFRB Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 82.8 kDa and the accession number...
TMPY-05608 PDGFRA Protein, Human, Recombinant (His & Avi), Biotinylated
PDGFRA Protein, Human, Recombinant (His & Avi), Biotinylated
Human HEK293 Cells
PDGFRA Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 59.4 ...
TMPY-05787 PDGFRA Protein, Mouse, Recombinant (His)
PDGFRA Protein, Mouse, Recombinant (His)
Mouse HEK293 Cells
PDGFRA Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.87 kDa and the accession numbe...
PDGF R alpha/PDGFRA Protein, Human, Recombinant (His & Avi)
TMPK-00419
Platelet-derived growth factor is commonly known as a mitogen. Many research data suggest a role for PDGF-beta R in the mitogenic response of mesangial cells. Th...
PDGF R alpha/PDGFRA Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00420
Platelet-derived growth factor is commonly known as a mitogen. Many research data suggest a role for PDGF-beta R in the mitogenic response of mesangial cells. Th...
PDGF R beta/CD140b Protein, Human, Recombinant (His & Avi)
TMPK-00421
PDGF R beta/CD140b Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 59 kDa an...
PDGF R beta/CD140b Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00422
PDGF R beta/CD140b Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weigh...
PDGF R beta/CD140b Protein, Cynomolgus, Recombinant (His)
TMPK-00481
Platelet-derived growth factor receptor (PDGFR) signaling is involved in proliferation and survival in a wide array of cell types.PDGFR-β signalling, via TGF-β s...
PDGF R alpha/PDGFRA Protein, Cynomolgus, Recombinant (His)
TMPK-00943
Platelet-derived growth factor is commonly known as a mitogen. Many research data suggest a role for PDGF-beta R in the mitogenic response of mesangial cells. Th...
PDGF R beta/CD140b Protein, Canine, Recombinant (His)
TMPK-01050
PDGF R beta/CD140b Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 57.25 kDa and the ...
PDGFRB Protein, Rhesus, Recombinant (hFc)
TMPY-00385
PDGFRB Protein, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 83.3 kDa and the accession numbe...
PDGFRA Protein, Human, Recombinant (hFc)
TMPY-00900
PDGFRA Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 82.9 kDa and the accession number...
PDGFRB Protein, Human, Recombinant (His)
TMPY-01207
PDGFRB Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.6 kDa and the accession number...
PDGFRB Protein, Rat, Recombinant (His)
TMPY-03140
PDGFRB Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.6 kDa and the accession number i...
PDGFRB Protein, Rat, Recombinant (hFc)
TMPY-03474
PDGFRB Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 83.2 kDa and the accession number i...
PDGFRB Protein, Rhesus, Recombinant (His)
TMPY-03590
PDGFRB Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.7 kDa and the accession numbe...
PDGFRA Protein, Rat, Recombinant (His)
TMPY-03825
PDGFRA Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.6 kDa and the accession number i...
PDGFRA Protein, Rat, Recombinant (hFc)
TMPY-03919
PDGFRA Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 83.2 kDa and the accession number i...
PDGFRB Protein, Human, Recombinant (His), Biotinylated
TMPY-04937
PDGFRB Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.6 kDa and the ac...
PDGFRB Protein, Human, Recombinant
TMPY-05358
PDGFRB Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 56.2 kDa and the accession number is P09619-1.
PDGFRB Protein, Human, Recombinant (hFc)
TMPY-05497
PDGFRB Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 82.8 kDa and the accession number...
PDGFRA Protein, Human, Recombinant (His & Avi), Biotinylated
TMPY-05608
PDGFRA Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 59.4 ...
PDGFRA Protein, Mouse, Recombinant (His)
TMPY-05787
PDGFRA Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.87 kDa and the accession numbe...
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