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Hematologic Malignancies Target Proteins

In hematological malignancies, CD19, BCMA, and CD22 are the most frequently studied target proteins. CD19 is the primary target for the treatment of B-cell blood cancers. BCMA and CD22 are both antigens expressed on the surface of B cells, and cell therapies targeting these two targets could be used to treat patients with B-cell blood cancers that have developed resistance to cell therapies targeting CD19. Other related targets under study include GPRC5D, CLEC12A and CD7.

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Species
Canine (3)
Cynomolgus (21)
Ferret (2)
Human (111)
Mouse (35)
Rabbit (2)
Rat (13)
Rhesus (16)
Rhesus Macaque (2)
Rhesus macaque (4)
Expression System
Baculovirus-Insect Cells (5)
CHO (1)
E. coli (4)
HEK293 (164)
Human Cells (23)
Tag
AVI (19)
C-6His (6)
C-6His-Avi (3)
C-6His-Flag (1)
C-Fc (7)
C-Flag (1)
C-His (8)
C-His-Avi (20)
C-hFc (4)
C-mFc (2)
FLAG (1)
Fc (2)
GST (1)
His (81)
N-6His (1)
N-6His-Flag (1)
N-Fc (1)
N-His-Avi (2)
N-hFc-Flag (2)
Tag Free (9)
TrxA (2)
hFc (43)
mFc (3)
rFc (1)
Cat No. product name / Synonyms Species Expression System
TMPY-04615 CD20 Protein, Human, Recombinant (TrxA)
CD20 Protein, Human, Recombinant (TrxA)
Human E. coli
CD20 (membrane-spanning 4-domains, subfamily A, member 1), also known as MS4A1, is a member of the membrane-spanning 4A gene family. Members of this nascent prot...
TMPY-04729 CD19 Protein, Cynomolgus, Rhesus, Recombinant (hFc)
CD19 Protein, Cynomolgus, Rhesus, Recombinant (hFc)
Cynomolgus,Rhesus HEK293
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified...
TMPY-04808 Siglec-3/CD33 Protein, Mouse, Recombinant
Siglec-3/CD33 Protein, Mouse, Recombinant
Mouse HEK293
Myeloid cell surface antigen CD33 also known as Sialic acid binding Ig-like lectin 3, CD33 antigen or Siglec-3, is a member of the immunoglobulin superfamily and...
TMPY-04959 CD4 Protein, Mouse, Recombinant (His), Biotinylated
CD4 Protein, Mouse, Recombinant (His), Biotinylated
Mouse HEK293
T-cell surface glycoprotein CD4, is a single-pass type I membrane protein. CD4 contains three Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-typ...
TMPY-04986 ROR1 Protein, Human, Recombinant, Biotinylated
ROR1 Protein, Human, Recombinant, Biotinylated
Human HEK293
ROR1 Protein, Human, Recombinant, Biotinylated is expressed in HEK293. The predicted molecular weight is 42.8 kDa. Accession number: Q01973
TMPY-05118 CD30/TNFRSF8 Protein, Human, Recombinant (His), Biotinylated
CD30/TNFRSF8 Protein, Human, Recombinant (His), Biotinylated
Human HEK293
CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor (TNFR) superfamily. CD30 protein is expressed by activated, but not...
TMPY-05127 CD19 Protein, Human, Recombinant (His), Biotinylated
CD19 Protein, Human, Recombinant (His), Biotinylated
Human HEK293
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified...
TMPY-05136 BCMA/TNFRSF17 Protein, Rhesus, Recombinant, Biotinylated
BCMA/TNFRSF17 Protein, Rhesus, Recombinant, Biotinylated
Rhesus HEK293
Tumor necrosis factor receptor superfamily, member 17 (TNFRSF17), also known as B cell maturation antigen (BCMA) or CD269 antigen, is a member of the TNF-recepto...
TMPY-05197 BCMA/TNFRSF17 Protein, Human, Recombinant (mFc)
BCMA/TNFRSF17 Protein, Human, Recombinant (mFc)
Human HEK293
Tumor necrosis factor receptor superfamily, member 17 (TNFRSF17), also known as B cell maturation antigen (BCMA) or CD269 antigen, is a member of the TNF-recepto...
TMPY-05223 Siglec-2/CD22 Protein, Human, Recombinant (His), Biotinylated
Siglec-2/CD22 Protein, Human, Recombinant (His), Biotinylated
Human HEK293
CD22 is a member of the immunoglobulin superfamily, SIGLEC family of lectins. It is first expressed in the cytoplasm of pro-B and pre-B cells, and on the surface...
TMPY-05273 CD38 Protein, Human, Recombinant (hFc)
CD38 Protein, Human, Recombinant (hFc)
Human HEK293
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified...
TMPY-05316 Siglec-2/CD22 Protein, Human, Recombinant (aa 176-687, His), Biotinylated
Siglec-2/CD22 Protein, Human, Recombinant (aa 176-687, His), Biotinylated
Human HEK293
CD22 is a member of the immunoglobulin superfamily, SIGLEC family of lectins. It is first expressed in the cytoplasm of pro-B and pre-B cells, and on the surface...
TMPY-05328 BCMA/TNFRSF17 Protein, Human, Recombinant (His & Avi)
BCMA/TNFRSF17 Protein, Human, Recombinant (His & Avi)
Human HEK293
Tumor necrosis factor receptor superfamily, member 17 (TNFRSF17), also known as B cell maturation antigen (BCMA) or CD269 antigen, is a member of the TNF-recepto...
TMPY-05366 Siglec-3/CD33 Protein, Cynomolgus, Rhesus, Recombinant (His), Biotinylated
Siglec-3/CD33 Protein, Cynomolgus, Rhesus, Recombinant (His), Biotinylated
Cynomolgus,Rhesus HEK293
Myeloid cell surface antigen CD33 also known as Sialic acid binding Ig-like lectin 3, CD33 antigen or Siglec-3, is a member of the immunoglobulin superfamily and...
TMPY-05381 Siglec-3/CD33 Protein, Human, Recombinant (hFc)
Siglec-3/CD33 Protein, Human, Recombinant (hFc)
Human HEK293
Myeloid cell surface antigen CD33 also known as Sialic acid binding Ig-like lectin 3, CD33 antigen or Siglec-3, is a member of the immunoglobulin superfamily and...
TMPY-05385 BCMA/TNFRSF17 Protein, Human, Recombinant (hFc)
BCMA/TNFRSF17 Protein, Human, Recombinant (hFc)
Human HEK293
Tumor necrosis factor receptor superfamily, member 17 (TNFRSF17), also known as B cell maturation antigen (BCMA) or CD269 antigen, is a member of the TNF-recepto...
TMPY-05387 SLAMF7 Protein, Human, Recombinant (hFc)
SLAMF7 Protein, Human, Recombinant (hFc)
Human HEK293
SLAM family member 7 (SLAMF7), also known as CRACC, CD319, CD2-like receptor-activating cytotoxic cells, and CS1, is a single-pass type I membrane protein and a ...
TMPY-05420 CD19 Protein, Cynomolgus, Rhesus, Recombinant (His)
CD19 Protein, Cynomolgus, Rhesus, Recombinant (His)
Cynomolgus,Rhesus HEK293
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified...
TMPY-05424 CD4 Protein, Rhesus, Recombinant (hFc)
CD4 Protein, Rhesus, Recombinant (hFc)
Rhesus HEK293
T-cell surface glycoprotein CD4, is a single-pass type I membrane protein. CD4 contains three Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-typ...
TMPY-05443 CD30/TNFRSF8 Protein, Mouse, Recombinant (His)
CD30/TNFRSF8 Protein, Mouse, Recombinant (His)
Mouse HEK293
CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor (TNFR) superfamily. CD30 protein is expressed by activated, but not...
CD20 Protein, Human, Recombinant (TrxA)
TMPY-04615
CD20 (membrane-spanning 4-domains, subfamily A, member 1), also known as MS4A1, is a member of the membrane-spanning 4A gene family. Members of this nascent prot...
CD19 Protein, Cynomolgus, Rhesus, Recombinant (hFc)
TMPY-04729
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified...
Siglec-3/CD33 Protein, Mouse, Recombinant
TMPY-04808
Myeloid cell surface antigen CD33 also known as Sialic acid binding Ig-like lectin 3, CD33 antigen or Siglec-3, is a member of the immunoglobulin superfamily and...
CD4 Protein, Mouse, Recombinant (His), Biotinylated
TMPY-04959
T-cell surface glycoprotein CD4, is a single-pass type I membrane protein. CD4 contains three Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-typ...
ROR1 Protein, Human, Recombinant, Biotinylated
TMPY-04986
ROR1 Protein, Human, Recombinant, Biotinylated is expressed in HEK293. The predicted molecular weight is 42.8 kDa. Accession number: Q01973
CD30/TNFRSF8 Protein, Human, Recombinant (His), Biotinylated
TMPY-05118
CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor (TNFR) superfamily. CD30 protein is expressed by activated, but not...
CD19 Protein, Human, Recombinant (His), Biotinylated
TMPY-05127
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified...
BCMA/TNFRSF17 Protein, Rhesus, Recombinant, Biotinylated
TMPY-05136
Tumor necrosis factor receptor superfamily, member 17 (TNFRSF17), also known as B cell maturation antigen (BCMA) or CD269 antigen, is a member of the TNF-recepto...
BCMA/TNFRSF17 Protein, Human, Recombinant (mFc)
TMPY-05197
Tumor necrosis factor receptor superfamily, member 17 (TNFRSF17), also known as B cell maturation antigen (BCMA) or CD269 antigen, is a member of the TNF-recepto...
Siglec-2/CD22 Protein, Human, Recombinant (His), Biotinylated
TMPY-05223
CD22 is a member of the immunoglobulin superfamily, SIGLEC family of lectins. It is first expressed in the cytoplasm of pro-B and pre-B cells, and on the surface...
CD38 Protein, Human, Recombinant (hFc)
TMPY-05273
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified...
Siglec-2/CD22 Protein, Human, Recombinant (aa 176-687, His), Biotinylated
TMPY-05316
CD22 is a member of the immunoglobulin superfamily, SIGLEC family of lectins. It is first expressed in the cytoplasm of pro-B and pre-B cells, and on the surface...
BCMA/TNFRSF17 Protein, Human, Recombinant (His & Avi)
TMPY-05328
Tumor necrosis factor receptor superfamily, member 17 (TNFRSF17), also known as B cell maturation antigen (BCMA) or CD269 antigen, is a member of the TNF-recepto...
Siglec-3/CD33 Protein, Cynomolgus, Rhesus, Recombinant (His), Biotinylated
TMPY-05366
Myeloid cell surface antigen CD33 also known as Sialic acid binding Ig-like lectin 3, CD33 antigen or Siglec-3, is a member of the immunoglobulin superfamily and...
Siglec-3/CD33 Protein, Human, Recombinant (hFc)
TMPY-05381
Myeloid cell surface antigen CD33 also known as Sialic acid binding Ig-like lectin 3, CD33 antigen or Siglec-3, is a member of the immunoglobulin superfamily and...
BCMA/TNFRSF17 Protein, Human, Recombinant (hFc)
TMPY-05385
Tumor necrosis factor receptor superfamily, member 17 (TNFRSF17), also known as B cell maturation antigen (BCMA) or CD269 antigen, is a member of the TNF-recepto...
SLAMF7 Protein, Human, Recombinant (hFc)
TMPY-05387
SLAM family member 7 (SLAMF7), also known as CRACC, CD319, CD2-like receptor-activating cytotoxic cells, and CS1, is a single-pass type I membrane protein and a ...
CD19 Protein, Cynomolgus, Rhesus, Recombinant (His)
TMPY-05420
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified...
CD4 Protein, Rhesus, Recombinant (hFc)
TMPY-05424
T-cell surface glycoprotein CD4, is a single-pass type I membrane protein. CD4 contains three Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-typ...
CD30/TNFRSF8 Protein, Mouse, Recombinant (His)
TMPY-05443
CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor (TNFR) superfamily. CD30 protein is expressed by activated, but not...
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TargetMol