Ephrins, also known as ephrin ligands or Eph family receptor interacting proteins, are a family of proteins that serve as the ligands of the Eph receptor. Eph receptors in turn compose the largest known subfamily of receptor protein-tyrosine kinases (RTKs). Since ephrin ligands (ephrins) and Eph receptors (Ephs) are both membrane-bound proteins, binding and activation of Eph/ephrin intracellular signaling pathways can only occur via direct cell–cell interaction. Eph/ephrin signaling regulates a variety of biological processes during embryonic development including the guidance of axon growth cones, formation of tissue boundaries, cell migration, and segmentation. Additionally, Eph/ephrin signaling has been identified to play a critical role in the maintenance of several processes during adulthood including long-term potentiation, angiogenesis, and stem cell differentiation.
Cat No. | product name / Synonyms | Species | Expression System |
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TMPJ-00085 | EFNA4 Protein, Human, Recombinant (hFc & His)
EFNA4 Protein, Human, Recombinant (hFc & His)
|
Human | Human Cells |
Ephrin-A4 is a member of the ephrin ligand family which binds members of the Eph receptor family. All ligands share a conserved extracellular sequence, which mos... | |||
TMPJ-00088 | EFNA1 Protein, Mouse, Recombinant (hFc & His)
EFNA1 Protein, Mouse, Recombinant (hFc & His)
|
Mouse | Human Cells |
Ephrin-A1 is a cell membrane protein and contains 1 ephrin RBD (ephrin receptor-binding) domain. EFNA1 belongs to the ephrin (EPH) family. The ephrins and EPH-re... | |||
TMPJ-00114 | EFNA3 Protein, Mouse, Recombinant (hFc)
EFNA3 Protein, Mouse, Recombinant (hFc)
|
Mouse | Human Cells |
Ephrins-A3 belongs the Ephrins ligand family which involved in a variety of biological processes, especially in the nervous system and in erythropoiesis. It is s... | |||
TMPJ-00224 | EFNB2 Protein, Mouse, Recombinant (hFc & His)
EFNB2 Protein, Mouse, Recombinant (hFc & His)
|
Mouse | Human Cells |
Ephrin-B2 is a single-pass type I membrane protein and it contains 1 ephrin RBD (ephrin receptor-binding) domain. Ephrin-B2 belongs to the ephrin (EPH) family an... | |||
TMPJ-00230 | EFNB1 Protein, Mouse, Recombinant (hFc & His)
EFNB1 Protein, Mouse, Recombinant (hFc & His)
|
Mouse | Human Cells |
Mouse Ephrin-B1 is a single-pass type I membrane protein which belongs to the ephrin family. It contains an ephrin RBD (ephrin receptor-binding) domain, and expr... | |||
TMPJ-00546 | EFNA1 Protein, Human, Recombinant (hFc)
EFNA1 Protein, Human, Recombinant (hFc)
|
Human | Human Cells |
Ephrin-A1 is a member of the A-type ephrin family of cell surface proteins that function as ligands for the A-type Eph receptor tyrosine kinase family. Ephrin-A1... | |||
TMPK-00223 | Ephrin B2/EFNB2 Protein, Human, Recombinant (hFc)
Ephrin B2/EFNB2 Protein, Human, Recombinant (hFc)
|
Human | HEK293 |
Ephrin-B2 controls platelet-derived growth factor receptor β (PDGFRβ) distribution in the VSMC plasma membrane, endocytosis, and signaling in a fashion that is h... | |||
TMPY-00447 | Ephrin B3/EFNB3 Protein, Mouse, Recombinant (His)
Ephrin B3/EFNB3 Protein, Mouse, Recombinant (His)
|
Mouse | HEK293 |
Ephrin B3 belongs to the ephrin family. Ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol ... | |||
TMPY-00598 | Ephrin B3/EFNB3 Protein, Mouse, Recombinant (hFc)
Ephrin B3/EFNB3 Protein, Mouse, Recombinant (hFc)
|
Mouse | HEK293 |
Ephrin B3 belongs to the ephrin family. Ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol ... | |||
TMPY-00696 | Ephrin A4/EFNA4 Protein, Human, Recombinant (hFc)
Ephrin A4/EFNA4 Protein, Human, Recombinant (hFc)
|
Human | HEK293 |
EPH-related receptor tyrosine kinase ligand 4 (Ephrin-A4) also known as EFNA4, is a member of the Ephrin family. The Eph family receptor interacting proteins (ep... | |||
TMPY-00791 | Ephrin A3/EFNA3 Protein, Human, Recombinant
Ephrin A3/EFNA3 Protein, Human, Recombinant
|
Human | HEK293 |
Ephrin-A3 also known as EPH-related receptor tyrosine kinase ligand 3 or EFNA3, is a member of the ephrin family. The Eph family receptor interacting proteins (e... | |||
TMPY-00793 | Ephrin A5/EFNA5 Protein, Human, Recombinant (hFc)
Ephrin A5/EFNA5 Protein, Human, Recombinant (hFc)
|
Human | HEK293 |
Ephrin-A5 also known as EFNA5, is a member of the Ephrin family. The Eph family receptor interacting proteins (ephrins) are a family of proteins that serve as th... | |||
TMPY-01042 | Ephrin A5/EFNA5 Protein, Human, Recombinant (His)
Ephrin A5/EFNA5 Protein, Human, Recombinant (His)
|
Human | HEK293 |
Ephrin-A5 also known as EFNA5, is a member of the Ephrin family. The Eph family receptor interacting proteins (ephrins) are a family of proteins that serve as th... | |||
TMPY-01171 | Ephrin B1/EFNB1 Protein, Human, Recombinant (His)
Ephrin B1/EFNB1 Protein, Human, Recombinant (His)
|
Human | HEK293 |
Ephrin-B1 also known as EFNB1, is a member of the ephrin family. The transmembrane- associated ephrin ligands and their Eph family of receptor tyrosine kinases a... | |||
TMPY-01210 | Ephrin A1/EFNA1 Protein, Human, Recombinant (His)
Ephrin A1/EFNA1 Protein, Human, Recombinant (His)
|
Human | HEK293 |
EPH-related receptor tyrosine kinase ligand 1 (abbreviated as Ephrin-A1) also known as ligand of eph-related kinase 1 or EFNA1, is a member of the ephrin (EPH) f... | |||
TMPY-01286 | Ephrin B1/EFNB1 Protein, Human, Recombinant (His & hFc)
Ephrin B1/EFNB1 Protein, Human, Recombinant (His & hFc)
|
Human | HEK293 |
Ephrin-B1 also known as EFNB1, is a member of the ephrin family. The transmembrane- associated ephrin ligands and their Eph family of receptor tyrosine kinases a... | |||
TMPY-01287 | Ephrin B2/EFNB2 Protein, Human, Recombinant (His & hFc)
Ephrin B2/EFNB2 Protein, Human, Recombinant (His & hFc)
|
Human | HEK293 |
EphrinB2 also known as EFNB2 is a member of the ephrin family. EphrinB2 is involved in establishing arterial versus venous identity and perhaps in anastamosing a... | |||
TMPY-01392 | Ephrin A3/EFNA3 Protein, Human, Recombinant (hFc)
Ephrin A3/EFNA3 Protein, Human, Recombinant (hFc)
|
Human | HEK293 |
Ephrin-A3 also known as EPH-related receptor tyrosine kinase ligand 3 or EFNA3, is a member of the ephrin family. The Eph family receptor interacting proteins (e... | |||
TMPY-01407 | Ephrin A3/EFNA3 Protein, Human, Recombinant (His)
Ephrin A3/EFNA3 Protein, Human, Recombinant (His)
|
Human | HEK293 |
Ephrin-A3 also known as EPH-related receptor tyrosine kinase ligand 3 or EFNA3, is a member of the ephrin family. The Eph family receptor interacting proteins (e... | |||
TMPY-01443 | Ephrin B2/EFNB2 Protein, Mouse, Recombinant (His)
Ephrin B2/EFNB2 Protein, Mouse, Recombinant (His)
|
Mouse | HEK293 |
EphrinB2 also known as EFNB2 is a member of the ephrin family. EphrinB2 is involved in establishing arterial versus venous identity and perhaps in anastamosing a... |