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Ephrin Family

Ephrins, also known as ephrin ligands or Eph family receptor interacting proteins, are a family of proteins that serve as the ligands of the Eph receptor. Eph receptors in turn compose the largest known subfamily of receptor protein-tyrosine kinases (RTKs). Since ephrin ligands (ephrins) and Eph receptors (Ephs) are both membrane-bound proteins, binding and activation of Eph/ephrin intracellular signaling pathways can only occur via direct cell–cell interaction. Eph/ephrin signaling regulates a variety of biological processes during embryonic development including the guidance of axon growth cones, formation of tissue boundaries, cell migration, and segmentation. Additionally, Eph/ephrin signaling has been identified to play a critical role in the maintenance of several processes during adulthood including long-term potentiation, angiogenesis, and stem cell differentiation.

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Species
Canine (3)
Danio rerio (zebrafish) (2)
Human (17)
Mouse (19)
Rat (10)
Rhesus (2)
Expression System
HEK293 (47)
Human Cells (6)
Tag
C-Fc (2)
C-Fc-6His (4)
C-hFc (1)
His (24)
Tag Free (3)
hFc (21)
Cat No. product name / Synonyms Species Expression System
TMPJ-00085 EFNA4 Protein, Human, Recombinant (hFc & His)
EFNA4 Protein, Human, Recombinant (hFc & His)
Human Human Cells
Ephrin-A4 is a member of the ephrin ligand family which binds members of the Eph receptor family. All ligands share a conserved extracellular sequence, which mos...
TMPJ-00088 EFNA1 Protein, Mouse, Recombinant (hFc & His)
EFNA1 Protein, Mouse, Recombinant (hFc & His)
Mouse Human Cells
Ephrin-A1 is a cell membrane protein and contains 1 ephrin RBD (ephrin receptor-binding) domain. EFNA1 belongs to the ephrin (EPH) family. The ephrins and EPH-re...
TMPJ-00114 EFNA3 Protein, Mouse, Recombinant (hFc)
EFNA3 Protein, Mouse, Recombinant (hFc)
Mouse Human Cells
Ephrins-A3 belongs the Ephrins ligand family which involved in a variety of biological processes, especially in the nervous system and in erythropoiesis. It is s...
TMPJ-00224 EFNB2 Protein, Mouse, Recombinant (hFc & His)
EFNB2 Protein, Mouse, Recombinant (hFc & His)
Mouse Human Cells
Ephrin-B2 is a single-pass type I membrane protein and it contains 1 ephrin RBD (ephrin receptor-binding) domain. Ephrin-B2 belongs to the ephrin (EPH) family an...
TMPJ-00230 EFNB1 Protein, Mouse, Recombinant (hFc & His)
EFNB1 Protein, Mouse, Recombinant (hFc & His)
Mouse Human Cells
Mouse Ephrin-B1 is a single-pass type I membrane protein which belongs to the ephrin family. It contains an ephrin RBD (ephrin receptor-binding) domain, and expr...
TMPJ-00546 EFNA1 Protein, Human, Recombinant (hFc)
EFNA1 Protein, Human, Recombinant (hFc)
Human Human Cells
Ephrin-A1 is a member of the A-type ephrin family of cell surface proteins that function as ligands for the A-type Eph receptor tyrosine kinase family. Ephrin-A1...
TMPK-00223 Ephrin B2/EFNB2 Protein, Human, Recombinant (hFc)
Ephrin B2/EFNB2 Protein, Human, Recombinant (hFc)
Human HEK293
Ephrin-B2 controls platelet-derived growth factor receptor β (PDGFRβ) distribution in the VSMC plasma membrane, endocytosis, and signaling in a fashion that is h...
TMPY-00447 Ephrin B3/EFNB3 Protein, Mouse, Recombinant (His)
Ephrin B3/EFNB3 Protein, Mouse, Recombinant (His)
Mouse HEK293
Ephrin B3 belongs to the ephrin family. Ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol ...
TMPY-00598 Ephrin B3/EFNB3 Protein, Mouse, Recombinant (hFc)
Ephrin B3/EFNB3 Protein, Mouse, Recombinant (hFc)
Mouse HEK293
Ephrin B3 belongs to the ephrin family. Ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol ...
TMPY-00696 Ephrin A4/EFNA4 Protein, Human, Recombinant (hFc)
Ephrin A4/EFNA4 Protein, Human, Recombinant (hFc)
Human HEK293
EPH-related receptor tyrosine kinase ligand 4 (Ephrin-A4) also known as EFNA4, is a member of the Ephrin family. The Eph family receptor interacting proteins (ep...
TMPY-00791 Ephrin A3/EFNA3 Protein, Human, Recombinant
Ephrin A3/EFNA3 Protein, Human, Recombinant
Human HEK293
Ephrin-A3 also known as EPH-related receptor tyrosine kinase ligand 3 or EFNA3, is a member of the ephrin family. The Eph family receptor interacting proteins (e...
TMPY-00793 Ephrin A5/EFNA5 Protein, Human, Recombinant (hFc)
Ephrin A5/EFNA5 Protein, Human, Recombinant (hFc)
Human HEK293
Ephrin-A5 also known as EFNA5, is a member of the Ephrin family. The Eph family receptor interacting proteins (ephrins) are a family of proteins that serve as th...
TMPY-01042 Ephrin A5/EFNA5 Protein, Human, Recombinant (His)
Ephrin A5/EFNA5 Protein, Human, Recombinant (His)
Human HEK293
Ephrin-A5 also known as EFNA5, is a member of the Ephrin family. The Eph family receptor interacting proteins (ephrins) are a family of proteins that serve as th...
TMPY-01171 Ephrin B1/EFNB1 Protein, Human, Recombinant (His)
Ephrin B1/EFNB1 Protein, Human, Recombinant (His)
Human HEK293
Ephrin-B1 also known as EFNB1, is a member of the ephrin family. The transmembrane- associated ephrin ligands and their Eph family of receptor tyrosine kinases a...
TMPY-01210 Ephrin A1/EFNA1 Protein, Human, Recombinant (His)
Ephrin A1/EFNA1 Protein, Human, Recombinant (His)
Human HEK293
EPH-related receptor tyrosine kinase ligand 1 (abbreviated as Ephrin-A1) also known as ligand of eph-related kinase 1 or EFNA1, is a member of the ephrin (EPH) f...
TMPY-01286 Ephrin B1/EFNB1 Protein, Human, Recombinant (His & hFc)
Ephrin B1/EFNB1 Protein, Human, Recombinant (His & hFc)
Human HEK293
Ephrin-B1 also known as EFNB1, is a member of the ephrin family. The transmembrane- associated ephrin ligands and their Eph family of receptor tyrosine kinases a...
TMPY-01287 Ephrin B2/EFNB2 Protein, Human, Recombinant (His & hFc)
Ephrin B2/EFNB2 Protein, Human, Recombinant (His & hFc)
Human HEK293
EphrinB2 also known as EFNB2 is a member of the ephrin family. EphrinB2 is involved in establishing arterial versus venous identity and perhaps in anastamosing a...
TMPY-01392 Ephrin A3/EFNA3 Protein, Human, Recombinant (hFc)
Ephrin A3/EFNA3 Protein, Human, Recombinant (hFc)
Human HEK293
Ephrin-A3 also known as EPH-related receptor tyrosine kinase ligand 3 or EFNA3, is a member of the ephrin family. The Eph family receptor interacting proteins (e...
TMPY-01407 Ephrin A3/EFNA3 Protein, Human, Recombinant (His)
Ephrin A3/EFNA3 Protein, Human, Recombinant (His)
Human HEK293
Ephrin-A3 also known as EPH-related receptor tyrosine kinase ligand 3 or EFNA3, is a member of the ephrin family. The Eph family receptor interacting proteins (e...
TMPY-01443 Ephrin B2/EFNB2 Protein, Mouse, Recombinant (His)
Ephrin B2/EFNB2 Protein, Mouse, Recombinant (His)
Mouse HEK293
EphrinB2 also known as EFNB2 is a member of the ephrin family. EphrinB2 is involved in establishing arterial versus venous identity and perhaps in anastamosing a...
EFNA4 Protein, Human, Recombinant (hFc & His)
TMPJ-00085
Ephrin-A4 is a member of the ephrin ligand family which binds members of the Eph receptor family. All ligands share a conserved extracellular sequence, which mos...
EFNA1 Protein, Mouse, Recombinant (hFc & His)
TMPJ-00088
Ephrin-A1 is a cell membrane protein and contains 1 ephrin RBD (ephrin receptor-binding) domain. EFNA1 belongs to the ephrin (EPH) family. The ephrins and EPH-re...
EFNA3 Protein, Mouse, Recombinant (hFc)
TMPJ-00114
Ephrins-A3 belongs the Ephrins ligand family which involved in a variety of biological processes, especially in the nervous system and in erythropoiesis. It is s...
EFNB2 Protein, Mouse, Recombinant (hFc & His)
TMPJ-00224
Ephrin-B2 is a single-pass type I membrane protein and it contains 1 ephrin RBD (ephrin receptor-binding) domain. Ephrin-B2 belongs to the ephrin (EPH) family an...
EFNB1 Protein, Mouse, Recombinant (hFc & His)
TMPJ-00230
Mouse Ephrin-B1 is a single-pass type I membrane protein which belongs to the ephrin family. It contains an ephrin RBD (ephrin receptor-binding) domain, and expr...
EFNA1 Protein, Human, Recombinant (hFc)
TMPJ-00546
Ephrin-A1 is a member of the A-type ephrin family of cell surface proteins that function as ligands for the A-type Eph receptor tyrosine kinase family. Ephrin-A1...
Ephrin B2/EFNB2 Protein, Human, Recombinant (hFc)
TMPK-00223
Ephrin-B2 controls platelet-derived growth factor receptor β (PDGFRβ) distribution in the VSMC plasma membrane, endocytosis, and signaling in a fashion that is h...
Ephrin B3/EFNB3 Protein, Mouse, Recombinant (His)
TMPY-00447
Ephrin B3 belongs to the ephrin family. Ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol ...
Ephrin B3/EFNB3 Protein, Mouse, Recombinant (hFc)
TMPY-00598
Ephrin B3 belongs to the ephrin family. Ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol ...
Ephrin A4/EFNA4 Protein, Human, Recombinant (hFc)
TMPY-00696
EPH-related receptor tyrosine kinase ligand 4 (Ephrin-A4) also known as EFNA4, is a member of the Ephrin family. The Eph family receptor interacting proteins (ep...
Ephrin A3/EFNA3 Protein, Human, Recombinant
TMPY-00791
Ephrin-A3 also known as EPH-related receptor tyrosine kinase ligand 3 or EFNA3, is a member of the ephrin family. The Eph family receptor interacting proteins (e...
Ephrin A5/EFNA5 Protein, Human, Recombinant (hFc)
TMPY-00793
Ephrin-A5 also known as EFNA5, is a member of the Ephrin family. The Eph family receptor interacting proteins (ephrins) are a family of proteins that serve as th...
Ephrin A5/EFNA5 Protein, Human, Recombinant (His)
TMPY-01042
Ephrin-A5 also known as EFNA5, is a member of the Ephrin family. The Eph family receptor interacting proteins (ephrins) are a family of proteins that serve as th...
Ephrin B1/EFNB1 Protein, Human, Recombinant (His)
TMPY-01171
Ephrin-B1 also known as EFNB1, is a member of the ephrin family. The transmembrane- associated ephrin ligands and their Eph family of receptor tyrosine kinases a...
Ephrin A1/EFNA1 Protein, Human, Recombinant (His)
TMPY-01210
EPH-related receptor tyrosine kinase ligand 1 (abbreviated as Ephrin-A1) also known as ligand of eph-related kinase 1 or EFNA1, is a member of the ephrin (EPH) f...
Ephrin B1/EFNB1 Protein, Human, Recombinant (His & hFc)
TMPY-01286
Ephrin-B1 also known as EFNB1, is a member of the ephrin family. The transmembrane- associated ephrin ligands and their Eph family of receptor tyrosine kinases a...
Ephrin B2/EFNB2 Protein, Human, Recombinant (His & hFc)
TMPY-01287
EphrinB2 also known as EFNB2 is a member of the ephrin family. EphrinB2 is involved in establishing arterial versus venous identity and perhaps in anastamosing a...
Ephrin A3/EFNA3 Protein, Human, Recombinant (hFc)
TMPY-01392
Ephrin-A3 also known as EPH-related receptor tyrosine kinase ligand 3 or EFNA3, is a member of the ephrin family. The Eph family receptor interacting proteins (e...
Ephrin A3/EFNA3 Protein, Human, Recombinant (His)
TMPY-01407
Ephrin-A3 also known as EPH-related receptor tyrosine kinase ligand 3 or EFNA3, is a member of the ephrin family. The Eph family receptor interacting proteins (e...
Ephrin B2/EFNB2 Protein, Mouse, Recombinant (His)
TMPY-01443
EphrinB2 also known as EFNB2 is a member of the ephrin family. EphrinB2 is involved in establishing arterial versus venous identity and perhaps in anastamosing a...
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TargetMol