Powder: -20°C for 3 years
In solvent: -80°C for 2 years
Vorasidenib is an inhibitor of mutant isocitrate dehydrogenase (IDH; IC50s = 31.9 and 31.7 nM for IDH1R132H and IDH2R140Q, respectively)
Description | Vorasidenib is an inhibitor of mutant isocitrate dehydrogenase (IDH; IC50s = 31.9 and 31.7 nM for IDH1R132H and IDH2R140Q, respectively) |
Targets&IC50 | IDH1R132H:31.9 nM , IDH2R140Q:31.7 nM |
In vivo | Vorsidenib reduces tumor growth in a TS603-IDH1R132H mouse xenograft model when administered at a dose of 50 mg/kg. |
Synonyms | PVM/MA共聚物, PVM/MA, AG-881 |
Molecular Weight | 414.74 |
Formula | C14H13ClF6N6 |
CAS No. | 1644545-52-7 |
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
DMSO: 125 mg/mL (301.39 mM)
( < 1 mg/ml refers to the product slightly soluble or insoluble )
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Vorasidenib 1644545-52-7 代谢 Isocitrate Dehydrogenase (IDH) inhibit PVM/MA AG 881 AG-881 AG881 Inhibitor inhibitor