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VU0155041

Name: VU0155041
Brand: TargetMol
SKU: T3565
Price: 34 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T3565Cas No. 1093757-42-6

Alias VU-0155041, UV0155041

VU0155041 is an effective and positive allosteric modulator/allosteric agonist at mGlu4 receptors (EC50: 798/693 nM, at human/rat).

VU0155041

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Purity: 99.56%

Catalog No. T3565Alias VU-0155041, UV0155041Cas No. 1093757-42-6

VU0155041 is an effective and positive allosteric modulator/allosteric agonist at mGlu4 receptors (EC50: 798/693 nM, at human/rat).

Pack Size	Price	Availability
2 mg	$34	In Stock
5 mg	$53	In Stock
10 mg	$77	In Stock
25 mg	$148	In Stock
50 mg	$198	In Stock
100 mg	$317	In Stock
200 mg	$458	In Stock
1 mL x 10 mM (in DMSO)	$58	In Stock

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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.56%

Resource Download

COA HNMR HPLC

Product Introduction

Bioactivity

Description	VU0155041 is an effective and positive allosteric modulator/allosteric agonist at mGlu4 receptors (EC50: 798/693 nM, at human/rat).
Targets&IC50	mGlu4 (human):798nM(EC50), mGlu4 (rat):693 nM(EC50)
Synonyms	VU-0155041, UV0155041

Chemical Properties

Molecular Weight	316.18
Formula	C₁₄H₁₅Cl₂NO₃
Cas No.	1093757-42-6
Smiles	OC(=O)[C@H]1CCCC[C@H]1C(=O)Nc1cc(Cl)cc(Cl)c1
Relative Density.	1.429 g/cm3 (Predicted)
Color	Red
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 31.6 mg/mL (99.94 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (6.33 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.1628 mL	15.8138 mL	31.6276 mL	158.1378 mL
5 mM	0.6326 mL	3.1628 mL	6.3255 mL	31.6276 mL
10 mM	0.3163 mL	1.5814 mL	3.1628 mL	15.8138 mL
20 mM	0.1581 mL	0.7907 mL	1.5814 mL	7.9069 mL
50 mM	0.0633 mL	0.3163 mL	0.6326 mL	3.1628 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc