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USP30 inhibitor 11

Catalog No. T13267 CAS 2067332-64-1

Synonyms: USP30-IN-11

USP30 inhibitor 11 (USP30-IN-11) is a selective USP30 inhibitor (IC50: 0.01 µΜ) that inhibits SVA and can be used in studies of cancer, mitochondrial dysfunction and Parkinson's.

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USP30 inhibitor 11, CAS 2067332-64-1

Pack Size	Availability	Price/USD
1 mg	In stock	$ 215.00
2 mg	In stock	$ 318.00
5 mg	In stock	$ 538.00
10 mg	In stock	$ 793.00
25 mg	In stock	$ 1,180.00
50 mg	In stock	$ 1,630.00
100 mg	In stock	$ 2,190.00

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Purity: 99.63%

Purity: 96.31%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	USP30 inhibitor 11 (USP30-IN-11) is a selective USP30 inhibitor (IC50: 0.01 µΜ) that inhibits SVA and can be used in studies of cancer, mitochondrial dysfunction and Parkinson's.
Targets&IC50	USP30:0.01 µΜ
In vitro	In the mitochondrial outer membrane, USP30 is a 517 amino acid protein found. It is the sole deubiquitylating enzyme bearing a mitochondrial addressing signal and has been shown to deubiquitylate a number of mitochondrial proteins[1].USP30 inhibitor 11 inhibits USP30 biochemical activity with an IC50 of 0.01 µΜ in a USP30 biochemical IC50 assay (0.01-30 µΜ; λEx=540 nm; λEm=590 nm) [1].

Synonyms	USP30-IN-11
Molecular Weight	368.41
Formula	C17H16N6O2S
CAS No.	2067332-64-1

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 20 mg/mL (54.29 mM), Sonication is recommended.

References and Literature

1. Mark Kemp, et al. Cyanopyrrolidines as dub inhibitors for the treatment of cancer. Patent WO 2017009650 A1.

Related compound libraries

This product is contained In the following compound libraries：

Inhibitor Library

Related Products

Related compounds with same targets

GNE-6640 GSK2643943A ML364 USP28-IN-3 BAY 11-7082 Vialinin A Spautin-1 USP8-IN-1

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

USP30 inhibitor 11 2067332-64-1 Cell Cycle/Checkpoint DNA Damage/DNA Repair Ubiquitination DUB USP30-IN-11 USP-30 inhibitor 11 inhibitor inhibit

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