Powder: -20°C for 3 years | In solvent: -80°C for 1 year
UK-124114 (Selamectin) is a macrocyclic lactone derivative of ivermectin, an anthelmintic that potentiates glutamate- and GABA-gated chloride channel opening in nematodes. In an H. contortus larval development assay, selamectin (0.1 μg/ml) shows the effect of growth inhibition.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 53.00 | |
5 mg | In stock | $ 118.00 | |
10 mg | In stock | $ 175.00 | |
25 mg | In stock | $ 289.00 | |
50 mg | In stock | $ 432.00 | |
100 mg | In stock | $ 639.00 |
Description | UK-124114 (Selamectin) is a macrocyclic lactone derivative of ivermectin, an anthelmintic that potentiates glutamate- and GABA-gated chloride channel opening in nematodes. In an H. contortus larval development assay, selamectin (0.1 μg/ml) shows the effect of growth inhibition. |
In vivo | A single administration of 6 mg/kg topical selamectin given every two months could effectively prevent B. malayi infection.?Application of topical selamectin twice a year could block circulating microfilariae.?Since there are no treatment guidelines currently available for lymphatic filarial infection in cats, the data obtained from this study could be used to guide the management of brugian lymphatic filarial infection in reservoir cats[3]. |
Synonyms | UNII-A2669OWX9N, Selamectin |
Molecular Weight | 769.96 |
Formula | C43H63NO11 |
CAS No. | 165108-07-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 5 mM
You can also refer to dose conversion for different animals. More
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UK-124114 165108-07-6 Others UK 124114 UNII-A2669OWX9N UK124114 Selamectin inhibitor inhibit