Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Tin-protoporphyrin IX is a potent inhibitor of Heme oxygenase-1 (HO-1). It sensitizes pancreatic ductal adenocarcinoma (PDAC) tumors to chemotherapy in mice models.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | 35 days | $ 123.00 | |
10 mg | 35 days | $ 230.00 | |
25 mg | 35 days | $ 540.00 | |
50 mg | 35 days | $ 950.00 |
Description | Tin-protoporphyrin IX is a potent inhibitor of Heme oxygenase-1 (HO-1). It sensitizes pancreatic ductal adenocarcinoma (PDAC) tumors to chemotherapy in mice models. |
Targets&IC50 | HO-1: |
In vitro | Tin-protoporphyrin IX with 20 μM, 50 μM and 24 hours, significantly suppressed the proliferation of Capan-1 and CD18/HPAF cells. In contrast. |
In vivo | Tin-protoporphyrin IX (5 mg/kg; at 0, 7, 15, and 20 days) intraperitoneal injection alone or combines with Gemcitabine significantly reduced the weight of pancreatic tumors (P < 0.05), decreases metastasis and improved the efficacy of Gemcitabine treatment. |
Synonyms | SnPPIX |
Molecular Weight | 749.26 |
Formula | C34H31Cl2N4O4Sn |
CAS No. | 14325-05-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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Tin-protoporphyrin IX 14325-05-4 Others Tinprotoporphyrin IX Tin protoporphyrin IX SnPPIX inhibitor inhibit