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Tasosartan

Catalog No. T7797 CAS 145733-36-4

Synonyms: WAY-ANA 756

Tasosartan (WAY-ANA 756) is an antagonist of angiotensin II type 2 (AT2) receptor (IC50 = 1.2 nM).

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Tasosartan, CAS 145733-36-4

Pack Size	Availability	Price/USD
1 mg	In stock	$ 51.00
2 mg	In stock	$ 74.00
5 mg	In stock	$ 122.00
10 mg	In stock	$ 197.00
25 mg	In stock	$ 333.00
50 mg	In stock	$ 497.00
100 mg	In stock	$ 693.00
1 mL * 10 mM (in DMSO)	In stock	$ 133.00

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Purity: 98.93%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Tasosartan (WAY-ANA 756) is an antagonist of angiotensin II type 2 (AT2) receptor (IC50 = 1.2 nM).
Targets&IC50	Ang II type 2 receptor:1.2 nM
In vivo	In vivo, tasosartan (p.o. or i.v.) blocked by 80% AT1 receptors 1 to 2 h after drug administration and still had a 40% effect at 32 h.

Synonyms	WAY-ANA 756
Molecular Weight	411.46
Formula	C23H21N7O
CAS No.	145733-36-4

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 125 mg/mL (303.80 mM)

References and Literature

1. Maillard M P , Rossat J , Brunner H R , et al. Tasosartan, enoltasosartan, and angiotensin II receptor blockade: The confounding role of protein binding[J]. Journal of Pharmacology & Experimental Therapeutics, 2000, 295(2):649-654. 2. Ellingboe J W , Collini M D , Quagliato D , et al. Metabolites of the Angiotensin II Antagonist Tasosartan:? The Importance of a Second Acidic Group[J]. journal of medicinal chemistry, 1998, 41(22):4251-4260.

Related compound libraries

This product is contained In the following compound libraries：

Inhibitor Library NO PAINS Compound Library Bioactive Compounds Library Max Anti-Hypertension Compound Library Human Metabolite Library Bioactive Compound Library Drug-induced Liver Injury (DILI) Compound Library Angiogenesis related Compound Library ReFRAME Related Library Endocrinology-Hormone Compound Library

Related Products

Related compounds with same targets

Angiotensin II human Angiotensin II human acetate C-Type Natriuretic Peptide (CNP) (1-22), human Eprosartan Ramiprilat Moexipril hydrochloride BTB06584 TRV055 acetate

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Tasosartan 145733-36-4 Endocrinology/Hormones RAAS Inhibitor WAY-ANA756 Angiotensin Receptor inhibit WAY-ANA-756 WAY-ANA 756 inhibitor

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.