Powder: -20°C for 3 years
In solvent: -80°C for 6 months
Tasosartan is an antagonist of angiotensin II type 2 (AT2) receptor (IC50 = 1.2 nM).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
2 mg | In stock | 95.00 | |
5 mg | In stock | 135.00 | |
10 mg | In stock | 219.00 | |
25 mg | In stock | 396.00 | |
50 mg | In stock | 594.00 | |
1 mL * 10 mM (in DMSO) | In stock | 145.00 |
Description | Tasosartan is an antagonist of angiotensin II type 2 (AT2) receptor (IC50 = 1.2 nM). |
Targets&IC50 | angiotensin II type 2 (AT2) receptor |
In vivo | In vivo, tasosartan (p.o. or i.v.) blocked by 80% AT1 receptors 1 to 2 h after drug administration and still had a 40% effect at 32 h. |
Animal Research |
Pressor response to angiotensin-II administration in four groups of rats (n=3-5 each, weighing 343±8 g). Each rat is subjected to four separate bolus injections of angiotensin-II following the introduction of either the vehicle or graded doses of Tasosartan (0.3, 1.0, or 3.0 mg/kg, iv) [2].
|
Molecular Weight | 411.46 |
Formula | C23H21N7O |
CAS No. | 145733-36-4 |
Powder: -20°C for 3 years
In solvent: -80°C for 6 months
DMSO: 125 mg/mL (303.80 mM)
( < 1 mg/ml refers to the product slightly soluble or insoluble )
You can also refer to dose conversion for different animals. More
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