Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Sclareolide (Norambreinolide) is a sesquiterpene lactone natural product derived from various plant sources including Salvia yosgadensis, Salvia sclarea, and cigar tobacco. It is a close analog of Sclareol, a plant antifungal compound.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
500 mg | In stock | $ 48.00 | |
1 g | In stock | $ 68.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 39.00 |
Description | Sclareolide (Norambreinolide) is a sesquiterpene lactone natural product derived from various plant sources including Salvia yosgadensis, Salvia sclarea, and cigar tobacco. It is a close analog of Sclareol, a plant antifungal compound. |
In vivo | Sclareolide is utilized in cosmetic fragrances and, despite the lack of clinical evidence, has recently been marketed as a weight loss product. |
Kinase Assay | Telomerase activity assay: The telomerase activity is measured by the TRAP assay using the TRAPez Telomerase Detection Kit, which includes primers of a 36-bp internal control (IC) for quantifying the amplification of telomerase activity within a linear range close to 2.5 logs. For RNase treatment, 10μL of extract are incubated with 1μg of RNase at 37 °C for 20 minutes. The products of the TRAP assay are resolved by electrophoresis in a nondenaturing12% PAGE in a buffer containing 0.5 × Tris–borate EDTA and detected by autoradiograph. For quantification of TRAP products, the dried gels are exposed to Fuji Imaging Plate at room temperature. Results are corrected for background, and a standard value of 100 is given to the untreated control cell signal. Signal intensities of Costunolide-treated cells are compared to the standard and are expressed as a fraction of the maximum value of 100. [1] |
Source |
Synonyms | Norambreinolide |
Molecular Weight | 250.38 |
Formula | C16H26O2 |
CAS No. | 564-20-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ethanol: 47 mg/mL (187.7 mM)
H2O: < 1 mg/mL (insoluble or slightly soluble)
DMSO: 47 mg/mL (187.7 mM)
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Sclareolide 564-20-5 Microbiology/Virology Others Antibacterial Escherichia coli Staphylococcus aureus inhibit Inhibitor Bacterial Norambreinolide Pseudomonas aeruginosa Enterococcus faecalis inhibitor