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Proctolin

Catalog No. TP1868 CAS 57966-42-4

Proctolin is a bioactive neuropeptide that modulates interneuronal and neuromuscular synaptic transmission in a wide variety of arthropods.

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Proctolin, CAS 57966-42-4

Pack Size	Availability	Price/USD
1 mg	In stock	$ 87.00
2 mg	In stock	$ 128.00
5 mg	In stock	$ 217.00
10 mg	In stock	$ 347.00
25 mg	In stock	$ 487.00
50 mg	In stock	$ 697.00
100 mg	In stock	$ 967.00

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Purity: 100%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Proctolin is a bioactive neuropeptide that modulates interneuronal and neuromuscular synaptic transmission in a wide variety of arthropods.

In vitro

Proctolin, an insect neuropeptide prevalent in arthropods, plays a significant role as a neuromodulator and potentially a neurohormone, although it doesn't act as a conventional neurotransmitter. It enhances action potential frequency, amplifies muscle contraction, and activates dormant systems. Structurally, Proctolin is a pentapeptide featuring the sequence RYLPT, notable for being the first insect neuropeptide with both sequenced and chemically characterized attributes. Identified first in D. melanogaster through the Proctolin precursor gene CG7105, it was previously undetected in B. mori due to lack of a mature peptide—attributed to missing cleavage sites around the RYLPT sequence. Recent proteomic analyses in B. mori wings have identified this pentapeptide, yet similar genetic characteristics in C. suppressalis suggest the absence of functional Proctolin in both species.

Molecular Weight	648.75
Formula	C30H48N8O8
CAS No.	57966-42-4

Storage

keep away from moisture

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 10mM

References and Literature

1. McGrath LL, et al. De novo transcriptome assembly for the lobster Homarus americanus and characterization of differential gene expression across nervous system tissues. BMC Genomics. 2016 Jan 16;17:63.

Related compound libraries

This product is contained In the following compound libraries：

Peptide Compound Library NO PAINS Compound Library Bioactive Compounds Library Max Human Metabolite Library Natural Product Library for HTS Natural Product Library Bioactive Compound Library

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Proctolin 57966-42-4 Others inhibit Inhibitor inhibitor

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