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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T4327 | Prexasertib dihydrochloride | LY2606368 (dihydrochloride) , Prexasertib HCl , LY2606368 | Chk , S6 Kinase , Apoptosis |
Prexasertib dihydrochloride (LY2606368) is an ATP-competitive CHK1 inhibitor (Ki: 0.9 nmol/L). in the cell-free assay, its IC50 values are 8 nM and 9 nM for CHK2 and RSK, respectively. |