Powder: -20°C for 3 years
In solvent: -80°C for 2 years
Pitavastatin is a potent inhibitor of HMG-CoA reductase (Ki: 1.7 nM). It lowers both total cholesterol and low-density lipoprotein cholesterol in animals and humans. Metabolism of pitavastatin by the cytochrome P450 system is minimal, reducing the risk of drug-drug interactions.
Description | Pitavastatin is a potent inhibitor of HMG-CoA reductase (Ki: 1.7 nM). It lowers both total cholesterol and low-density lipoprotein cholesterol in animals and humans. Metabolism of pitavastatin by the cytochrome P450 system is minimal, reducing the risk of drug-drug interactions. |
Targets&IC50 | HMG-CoA:5.8 nM |
Synonyms | Pitavastatin hemicalcium, NK-104, 匹伐他汀钙, itavastatin, nisvastatin, P-872441 |
Molecular Weight | 880.999 |
Formula | C50H46CaF2N2O8 |
CAS No. | 147526-32-7 |
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
DMSO: 44.1 mg/mL (100 mM)
( < 1 mg/ml refers to the product slightly soluble or insoluble )
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Pitavastatin calcium 147526-32-7 代谢 凋亡 自噬 Apoptosis Autophagy Endogenous Metabolite HMG-CoA Reductase Mitophagy Pitavastatin hemicalcium HMG-CoA Reductase (HMGCR) inhibit Inhibitor itavastatin nisvastatin NK-104 hemicalcium NK-104 Mitochondrial Autophagy P-872441 Pitavastatin inhibitor