Powder: -20°C for 3 years | In solvent: -80°C for 1 year
PKR-IN-C16 is a specific protein kinase (PKR) inhibitor. PKR-IN-C16 is able to inhibit the autophosphorylation of PKR and unlock the translation blockade induced by PKR in primary neuronal cultures.PKR-IN-C16 binds the ATP-binding site of PKR and blocks autophosphorylation with an IC50 value of 186-210 nM. PKR-IN-C16 protects human neuroblastoma cells against cell damage triggered by tunicamycin-mediated endoplasmic reticulum stress.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 36.00 | |
2 mg | In stock | $ 51.00 | |
5 mg | In stock | $ 80.00 | |
10 mg | In stock | $ 139.00 | |
25 mg | In stock | $ 289.00 | |
50 mg | In stock | $ 455.00 | |
100 mg | In stock | $ 672.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 113.00 |
Description | PKR-IN-C16 is a specific protein kinase (PKR) inhibitor. PKR-IN-C16 is able to inhibit the autophosphorylation of PKR and unlock the translation blockade induced by PKR in primary neuronal cultures.PKR-IN-C16 binds the ATP-binding site of PKR and blocks autophosphorylation with an IC50 value of 186-210 nM. PKR-IN-C16 protects human neuroblastoma cells against cell damage triggered by tunicamycin-mediated endoplasmic reticulum stress. |
Molecular Weight | 268.29 |
Formula | C13H8N4OS |
CAS No. | 608512-97-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 15.67 mg/mL(58.41 mM)
You can also refer to dose conversion for different animals. More
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PKR-IN-C16 608512-97-6 Others Inhibitor PKR inhibit PKRINC16 PKR-IN-C-16 SH-SY5Y acute brain lesions PKR IN C16 Apoptosis inhibitor