Powder: -20°C for 3 years | In solvent: -80°C for 1 year
PF-04745637 is a potent and selective TRPA1 antagonist with an IC50 of 17 nM[1].
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 112.00 | |
5 mg | In stock | $ 247.00 | |
10 mg | In stock | $ 345.00 | |
25 mg | In stock | $ 583.00 | |
50 mg | In stock | $ 833.00 | |
100 mg | In stock | $ 1,150.00 | |
500 mg | In stock | $ 2,290.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 277.00 |
Description | PF-04745637 is a potent and selective TRPA1 antagonist with an IC50 of 17 nM[1]. |
Targets&IC50 | TRPA1:17 nM |
In vivo | PF-04745637 (topically applied; 50 mg/mL and 100 mg/mL) significantly reduces cinnamaldehyde-mediated flare in rat skin[1]. |
Synonyms | PF4745637, PF 4745637, PF 04745637, PF-4745637 |
Molecular Weight | 509 |
Formula | C27H32ClF3N2O2 |
CAS No. | 1917294-46-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 60 mg/mL (117.88 mM)
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
PF-04745637 1917294-46-2 Membrane transporter/Ion channel TRP/TRPV Channel PF4745637 Inhibitor PF 4745637 PF 04745637 bowel PF-4745637 TRPA1 disease inhibit respiratory Transient receptor potential channels PF04745637 inflammatory TRP Channel skin inhibitor