Powder: -20°C for 3 years | In solvent: -80°C for 1 year
NH-bis(C2-PEG1-azide) is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
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Description | NH-bis(C2-PEG1-azide) is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. |
In vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Molecular Weight | 243.27 |
Formula | C8H17N7O2 |
CAS No. | 2100306-81-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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NH-bis(C2-PEG1-azide) 2100306-81-6 Others NHbis(C2PEG1azide) NH-bis(C-2-PEG1-azide) NH bis(C2 PEG1 azide) inhibitor inhibit