Powder: -20°C for 3 years | In solvent: -80°C for 1 year
NCGC00135472 (DRV1 (GPR32) agonist C2A) is a human Resolvin DI receptor DRV1 agonist with pro-catabolic properties that activates the human soluble protein D1 receptor DRV1/GPR32 receptor in beta-blocker and cAMP assays with EC50s of 0.37 uM and 0.05 uM, respectively.NCGC00135472 induces in cells overexpressing recombinant DRV1 rapid impedance changes that stimulate phagocytosis of serum-treated zymoglycans.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 350.00 | |
5 mg | In stock | $ 828.00 | |
10 mg | In stock | $ 1,130.00 | |
25 mg | In stock | $ 1,590.00 | |
50 mg | In stock | $ 1,980.00 | |
100 mg | In stock | $ 2,500.00 | |
500 mg | In stock | $ 4,900.00 |
Description | NCGC00135472 (DRV1 (GPR32) agonist C2A) is a human Resolvin DI receptor DRV1 agonist with pro-catabolic properties that activates the human soluble protein D1 receptor DRV1/GPR32 receptor in beta-blocker and cAMP assays with EC50s of 0.37 uM and 0.05 uM, respectively.NCGC00135472 induces in cells overexpressing recombinant DRV1 rapid impedance changes that stimulate phagocytosis of serum-treated zymoglycans. |
Targets&IC50 | cAMP:0.05 μM, β-arrestin:0.37 μM |
In vitro | We implemented a high-throughput screening of small molecule libraries and identified chemotypes that activated recombinant DRV1, including NCGC00135472 (C2A). NCGC00135472 (100 nM to 10 mM) dose-dependently elicited rapid changes in impedance with CHO-DRV1.[1] |
Synonyms | NCGC 00135472, DRV1 (GPR32) agonist C2A, C2A, NCGC-00135472 |
Molecular Weight | 364.35 |
Formula | C20H14F2N4O |
CAS No. | 862811-76-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 1.8 mg/mL (5.0 mM)
You can also refer to dose conversion for different animals. More
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NCGC00135472 862811-76-5 Others NCGC 00135472 DRV1 (GPR32) agonist C2A C2A NCGC-00135472 inhibitor inhibit