Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Manumycin A is an antibiotic. Manumycin A induces apoptosis and exerts antitumor activity. Manumycin A inhibits exosome biogenesis and secretion via targeted inhibition of Ras/Raf/ERK1/2 signaling. Manumycin A acts as a selective, competitive inhibitor of protein farnesyltransferase (FTase) with respect to farnesylpyrophosphate (Ki =1.2 μM), and as a noncompetitive inhibitor with respect to the Ras protein.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | 4-5 weeks | $ 278.00 | |
5 mg | 4-5 weeks | $ 987.00 |
Description | Manumycin A is an antibiotic. Manumycin A induces apoptosis and exerts antitumor activity. Manumycin A inhibits exosome biogenesis and secretion via targeted inhibition of Ras/Raf/ERK1/2 signaling. Manumycin A acts as a selective, competitive inhibitor of protein farnesyltransferase (FTase) with respect to farnesylpyrophosphate (Ki =1.2 μM), and as a noncompetitive inhibitor with respect to the Ras protein. |
Molecular Weight | 550.64 |
Formula | C31H38N2O7 |
CAS No. | 52665-74-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Manumycin A 52665-74-4 GPCR/G Protein Immunology/Inflammation Prostaglandin Receptor inhibitor inhibit