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MG 149

Catalog No. T6584 CAS 1243583-85-8

Synonyms: MG149, Tip60 HAT inhibitor

MG149 is a selective and potent Tip60 inhibitor with IC50 of 74 uM, similar potentcy for MOF(IC50= 47 uM).

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

MG 149, CAS 1243583-85-8

Pack Size	Availability	Price/USD
1 mg	In stock	$ 62.00
5 mg	In stock	$ 122.00
10 mg	In stock	$ 198.00
25 mg	In stock	$ 364.00
1 mL * 10 mM (in DMSO)	In stock	$ 134.00

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Purity: 98.28%

Purity: 99.1%

Purity: 98.69%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	MG149 is a selective and potent Tip60 inhibitor with IC50 of 74 uM, similar potentcy for MOF(IC50= 47 uM).
Targets&IC50	MOF:47 μM, Tip60:74 μM

Synonyms	MG149, Tip60 HAT inhibitor
Molecular Weight	340.463
Formula	C22H28O3
CAS No.	1243583-85-8

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

Ethanol: 63 mg/mL (185 mM)

H2O: <1 mg/mL

DMSO: 63 mg/mL (185 mM)

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Ghizzoni M, et al. 6-alkylsalicylates are selective Tip60 inhibitors and target the acetyl-CoA binding site. Eur J Med Chem. 2012 Jan;47(1):337-44.

Related compound libraries

This product is contained In the following compound libraries：

Bioactive Compounds Library Max Bioactive Compound Library Anti-Hypertension Compound Library NO PAINS Compound Library Reprogramming Compound Library Inhibitor Library Epigenetics Compound Library Anti-Aging Compound Library Apoptosis Compound Library Histone Modification Compound Library

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Related compounds with same targets

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

MG 149 1243583-85-8 Apoptosis Chromatin/Epigenetic Others Epigenetic Reader Domain Histone Acetyltransferase HAT Inhibitor MG149 HATs Tip60 HAT inhibitor inhibit MG-149 inhibitor

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