Powder: -20°C for 3 years
In solvent: -80°C for 2 years
Lithocholic acid is a bile acid formed from chenodeoxycholate by bacterial action, usually conjugated with glycine or taurine. It acts as a detergent to solubilize fats for absorption and is itself absorbed. It is used as cholagogue and choleretic.
Description | Lithocholic acid is a bile acid formed from chenodeoxycholate by bacterial action, usually conjugated with glycine or taurine. It acts as a detergent to solubilize fats for absorption and is itself absorbed. It is used as cholagogue and choleretic. |
Kinase Assay | Competitive ligand binding assay.: Ligand binding is performed using lysates from COS-7 cells transfected with expression plasmids for VDR or RXRα. Binding is performed overnight at 4°C in lysate buffer with 0.71 nM (18 Ci/mmol) [3H]1,25(OH)2D3 and bile acid competitor. Unbound [3H]1,25(OH)2D3 is removed by adsorption to dextran-coated charcoal and the supernatant removed for scintillation counting. Ki values are calculated from a computer fit of competition curves from triplicate assays. |
Synonyms | 3α-Hydroxy-5β-cholanic acid |
Molecular Weight | 376.58 |
Formula | C24H40O3 |
CAS No. | 434-13-9 |
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
Ethanol: 44 mg/mL (116.8 mM)
DMSO: 70 mg/mL (185.9 mM)
H2O: <1 mg/mL
( < 1 mg/ml refers to the product slightly soluble or insoluble )
You can also refer to dose conversion for different animals. More
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Lithocholic acid 434-13-9 Apoptosis Autophagy Metabolism Others Endogenous Metabolite FXR inhibit 3α-Hydroxy-5β-cholanic acid Inhibitor inhibitor