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Levofloxacin hydrate

Catalog No. T1451 CAS 138199-71-0

Synonyms: Levaquin hydrate, Cravit hydrate, Quixin hydrate, Levofloxacin Hemihydrate, Tavanic hydrate, Iquix hydrate

Levofloxacin hydrate (Cravit hydrate) is a broad-spectrum, third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin with antibacterial activity. Levofloxacin diffuses through the bacterial cell wall and acts by inhibiting DNA gyrase (bacterial topoisomerase II), an enzyme required for DNA replication, RNA transcription, and repair of bacterial DNA. Inhibition of DNA gyrase activity leads to blockage of bacterial cell growth.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

Levofloxacin hydrate, CAS 138199-71-0

Pack Size	Availability	Price/USD
50 mg	In stock	$ 40.00
100 mg	In stock	$ 48.00
1 mL * 10 mM (in DMSO)	In stock	$ 50.00

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Purity: 98.56%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Cell Research

Cell suspension samples (50 mL) (2-5×104 mast cells in each tube for dispersed skin cells or 1 ×105 mast cells in each tube for rat peritoneal cells) in duplicate are equilibrated at 37℃ for 10 min, and then added to polypropylene tubes containing 450 mL test compounds dissolved in Tyrode solution. Histamine release reaction is allowed to proceed for a further 30 min. at the end of which time the reaction is terminated by adding 2 mL ice-cold Tyrode solution and the mixture is centrifuged (450 g for 5 min at 4℃). For determination of total histamine content, mast cells are disrupted in boiling water for 10 min. Histamine concentrations in the resulting supernatant and disrupted cells are determined by the enzyme immunoassay described above. (Only for Reference)

Synonyms	Levaquin hydrate, Cravit hydrate, Quixin hydrate, Levofloxacin Hemihydrate, Tavanic hydrate, Iquix hydrate
Molecular Weight	370.38
Formula	C18H20FN3O4·1/2H2O
CAS No.	138199-71-0

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 74 mg/mL (199.79 mM)

H2O: 5 mg/mL (13.5 mM)

Ethanol: 10 mg/mL (27 mM)

Methanol: 10 mM

References and Literature

1. Schmitz FJ, et al. J Antimicrob ChemOthers. 1998 Apr;41(4):481-4.

Related compound libraries

This product is contained In the following compound libraries：

EMA Approved Drug Library Drug Repurposing Compound Library Inhibitor Library Anti-Infection Compound Library Immunology/Inflammation Compound Library Anti-Aging Compound Library Antibiotics Library Clinical Compound Library FDA-Approved & Pharmacopeia Drug Library Orally Active Compound Library

Related Products

Related compounds with same targets

Fleroxacin Tryptanthrin Trovafloxacin Novobiocin Sodium Zoliflodacin Enoxacin hydrate Sparfloxacin Levofloxacin hydrochloride

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Levofloxacin hydrate 138199-71-0 DNA Damage/DNA Repair Microbiology/Virology Antibiotic Antibacterial Topoisomerase DNA gyrase inhibit BK Viremia Levofloxacin Hydrate Quixin Hydrate chronic periodontitis Levaquin hydrate Inhibitor Iquix Hydrate Tavanic Hydrate Cravit hydrate Cravit Hydrate DNA/RNA Synthesis Quixin hydrate Levofloxacin Hemihydrate airway inflammation Tavanic hydrate Levofloxacin Bacterial Iquix hydrate Levaquin Hydrate inhibitor

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