Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Lck inhibitor 2 is a bis-anilinopyrimidine inhibitor of tyrosine kinases including LCK, BTK, LYN, SYK, and TXK (IC50s: 13nM, 9nM, 3nM, 26nM, and 2nM for Lck, Btk, Lyn, Btk, and Txk respectively).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
2 mg | 5 days | $ 68.00 | |
5 mg | 5 days | $ 128.00 | |
1 mL * 10 mM (in DMSO) | 5 days | $ 133.00 |
Description | Lck inhibitor 2 is a bis-anilinopyrimidine inhibitor of tyrosine kinases including LCK, BTK, LYN, SYK, and TXK (IC50s: 13nM, 9nM, 3nM, 26nM, and 2nM for Lck, Btk, Lyn, Btk, and Txk respectively). |
In vitro | A further 27 kinases were bound with %control < 10. Kd values for 16 kinases were determined and found to be below 100 nM. These included TXK (10 nM). Src family kinase Lck inhibitor 2 inhibited 48 kinases with %control < 1 (33 of them tyrosine kinases, almost half of the 71 tyrosine kinases in the panel) [2]. |
Molecular Weight | 335.36 |
Formula | C18H17N5O2 |
CAS No. | 944795-06-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 20 mg/mL (59.64 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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Lck inhibitor 2 944795-06-6 Others inhibitor inhibit