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LY2452473

Catalog No. T15804 CAS 1029692-15-6

LY2452473 is an orally bioavailable and selective androgen receptor modulator.

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LY2452473, CAS 1029692-15-6

Pack Size	Availability	Price/USD
2 mg	5 days	$ 52.00
5 mg	5 days	$ 89.00
10 mg	5 days	$ 122.00
1 mL * 10 mM (in DMSO)	5 days	$ 98.00

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Biological Description

Chemical Properties

Storage & Solubility Information

Description	LY2452473 is an orally bioavailable and selective androgen receptor modulator.
In vivo	LY2452473 is being developed for the treatment of disorders related to hypogonadism. LY2452473 is absorbed rapidly (time to reach maximum plasma concentration for both LY2452473 and total radioactivity is 2-3 h) and cleared slowly (plasma terminal t1/2 of 27 h for LY2452473 and 51 h for the total radioactivity).

Molecular Weight	374.44
Formula	C22H22N4O2
CAS No.	1029692-15-6

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 62.5 mg/mL (166.92 mM), Sonification is recommended.

References and Literature

1. Yi P, et al. Disposition and metabolism of LY2452473, a selective androgen receptor modulator, in humans. Drug Metab Dispos. 2012 Dec;40(12):2354-64.

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

LY2452473 1029692-15-6 MAPK Raf LY-2452473 LY 2452473 inhibitor inhibit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.