Powder: -20°C for 3 years
In solvent: -80°C for 2 years
Hydroxybupropion is the major active metabolite of Bupropion and an antagonist of nACh receptor. Hydroxybupropion inhibits <a href="/target/Norepinephrine" style="display: inline; color: #c13a36">Norepinephrine</a> uptake (IC50 = 1.7 μM).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 147.00 | |
2 mg | In stock | $ 217.00 | |
5 mg | In stock | $ 331.00 | |
10 mg | In stock | $ 519.00 | |
25 mg | In stock | $ 868.00 | |
50 mg | In stock | $ 1,298.00 | |
100 mg | In stock | $ 1,938.00 | |
200 mg | In stock | $ 2,925.00 |
Description | Hydroxybupropion is the major active metabolite of Bupropion and an antagonist of nACh receptor. Hydroxybupropion inhibits norepinephrine uptake (IC50 = 1.7 μM). |
Targets&IC50 | Norepinephrine uptake:1.7 μM |
In vitro | Hydroxybupropion shows stronger antitetrabenazine activity and has a lower LD50 value than the erythro- and threo- metabolites. Hydroxybupropion inhibits norepinephrine and dopamine uptake, antagonizes nicotine, and shows antidepressant effects in rodents[1]. |
Synonyms | Hydroxybupropione, 6-Hydroxybupropion, Hydroxybupropion, (+/-)- |
Molecular Weight | 255.74 |
Formula | C13H18ClNO2 |
CAS No. | 92264-81-8 |
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
DMSO: 90mg/mL (351.9mM), Need ultrasonic
( < 1 mg/ml refers to the product slightly soluble or insoluble )
You can also refer to dose conversion for different animals. More
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Hydroxybupropion 92264-81-8 Neuroscience AChR Norepinephrine Hydroxybupropione 6-Hydroxybupropion Hydroxybupropion, (+/-)- Inhibitor inhibitor inhibit