Powder: -20°C for 3 years | In solvent: -80°C for 1 year
HS-PEG7-CH2CH2COOH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
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Description | HS-PEG7-CH2CH2COOH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. |
In vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Synonyms | Thiol-PEG7-propionic acid |
Molecular Weight | 414.51 |
Formula | C17H34O9S |
CAS No. | T18027 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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HS-PEG7-CH2CH2COOH T18027 Others HSPEG7CH2CH2COOH HS PEG7 CH2CH2COOH HS-PEG-7-CH2CH2COOH Thiol-PEG7-propionic acid inhibitor inhibit