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FDI-6 is an effective and selective inhibitor of FOXM1 that blocks DNA binding. FDI-6(FDI6) binds to the FOXM1 protein and specifically downregulates FOXM1-activated genes.

| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $31 | In Stock | |
| 5 mg | $72 | In Stock | |
| 10 mg | $123 | In Stock | |
| 25 mg | $213 | In Stock | |
| 50 mg | $305 | In Stock | |
| 100 mg | $453 | In Stock | |
| 200 mg | $663 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $80 | In Stock |
| Description | FDI-6 is an effective and selective inhibitor of FOXM1 that blocks DNA binding. FDI-6(FDI6) binds to the FOXM1 protein and specifically downregulates FOXM1-activated genes. |
| In vitro | FDI-6 specifically downregulates FOXM1-activated genes with FOXM1 occupancy confirmed by ChIP-PCR. This small molecule-mediated effect is selective for FOXM1-controlled genes with no effect on genes regulated by homologous forkhead family factors. |
| Synonyms | FDI6, FDI 6 |
| Molecular Weight | 437.43 |
| Formula | C19H11F4N3OS2 |
| Cas No. | 313380-27-7 |
| Smiles | Nc1c(sc2nc(cc(c12)C(F)(F)F)-c1cccs1)C(=O)Nc1ccc(F)cc1 |
| Relative Density. | 1.562 g/cm3 (Predicted) |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 50 mg/mL (114.3 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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