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Ethylparaben

Catalog No. T0834 CAS 120-47-8

Synonyms: Ethyl 4-hydroxybenzoate, Ethyl parahydroxybenzoate

Ethylparaben is a Standardized Chemical Allergen. The physiologic effect of ethylparaben is by means of Increased Histamine Release, and Cell-mediated Immunity.

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Ethylparaben, CAS 120-47-8

Pack Size	Availability	Price/USD	Quantity
100 mg	In stock	$ 50.00
1 mL * 10 mM (in DMSO)	In stock	$ 50.00

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Purity: 99.9%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Ethylparaben is a Standardized Chemical Allergen. The physiologic effect of ethylparaben is by means of Increased Histamine Release, and Cell-mediated Immunity.
In vitro	Ethylparaben has weak estrogenic and weak anti-androgenic effects in vitro[2].
In vivo	In vivo studies indicate that ethylparaben has estrogenic effects in vivo in immature and ovariotectomized mice. A study on fetal exposure to ethylparaben revealed no changes in male anogenital distance and no changes of fetal testosterone production, but changes in gene expression levels pointed to subtle endocrine disrupting effects. A limited study in young male rats found no adverse effects, although tendencies to lower sperm counts are seen. Ethylparaben causes vitellogenin induction in fish[2].

Synonyms	Ethyl 4-hydroxybenzoate, Ethyl parahydroxybenzoate
Molecular Weight	166.176
Formula	C9H10O3
CAS No.	120-47-8

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

H2O: <1 mg/mL

DMSO: 31 mg/mL (186.6 mM)

Ethanol: 31 mg/mL (186.6 mM)

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Frederiksen H, et al. Toxicol Sci. 2008, 106(2):376-83. 2. Evaluation of tebuconazole, triclosan, methylparaben and ethylparaben according to the Danish proposal for criteria for endocrine disrupters, May 2012.

Related compound libraries

This product is contained In the following compound libraries：

Bioactive Compound Library Bioactive Compounds Library Max FDA-Approved & Pharmacopeia Drug Library Inactive Ingredient Library Anti-Bacterial Compound Library Human Metabolite Library The Yao nationality medicine Library NMPA-Approved Drug Library Drug Repurposing Compound Library Approved Drug Library

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Ethylparaben 120-47-8 Microbiology/Virology Antibacterial Antifungal Inhibitor inhibit Bacterial Ethyl 4-hydroxybenzoate Ethyl parahydroxybenzoate inhibitor

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