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Duocarmycin TM

Catalog No. T11120 CAS 157922-77-5

Duocarmycin TM is a DNA alkylator. Duocarmycin TM is an exceptionally potent antitumor antibiotic.

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Duocarmycin TM, CAS 157922-77-5

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Duocarmycin TM is a DNA alkylator. Duocarmycin TM is an exceptionally potent antitumor antibiotic.

Molecular Weight	466.91
Formula	C25H23ClN2O5
CAS No.	157922-77-5

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

DMSO: 50 mg/mL (107.09 mM)

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Dale L. Boger, et al. Critical Role of the Linking Amide in CC-1065 and the Duocarmycins: Implications on the Source of DNA Alkylation Catalysis. J. Am. Chem. Soc. 1998, 120, 11554-11557.

Related Products

Related compounds with same targets

Salinomycin sodium salt Cefozopran Amorolfine HCL Nanchangmycin Dicloxacillin Sodium Clindamycin palmitate hydrochloride Bismuth Subcitrate Potassium Amikacin hydrate

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Duocarmycin TM 157922-77-5 DNA损伤和修复微生物学 Antibiotic DNA Alkylation DNA Alkylator/Crosslinker alkylation Inhibitor ADC Cytotoxin BJAB cell inhibit duplex DNA CBI-TMI Antitumor ADC Payload WSU-DLCL2 cell inhibitor

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