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Direct Violet 1

Catalog No. T20033 CAS 2586-60-9

Synonyms: NSC-75778, CCRIS 2413, Airedale Violet ND, NSC 75778, NSC75778, Direct Violet N, 直接青莲N

Direct Violet 1 is an agent of dye.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

Direct Violet 1, CAS 2586-60-9

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Direct Violet 1 is an agent of dye.
Targets&IC50	SARS-CoV-S1S2 binding to ACE2:2.63 µM (IC50), TNF-R1-TNFα binding:2.11 µM (IC50), SARS-CoV-2-S-RBD binding to ACE2:1.47 µM (IC50)

Synonyms	NSC-75778, CCRIS 2413, Airedale Violet ND, NSC 75778, NSC75778, Direct Violet N, 直接青莲N
Molecular Weight	728.66
Formula	C32H22N6Na2O8S2
CAS No.	2586-60-9

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

DMSO: 55 mg/ml (75.48 mM)

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Banino A, Barry C, Uria B, Blundell C, Lillicrap T, Mirowski P, Pritzel A, Chadwick MJ, Degris T, Modayil J, Wayne G, Soyer H, Viola F, Zhang B, Goroshin R, Rabinowitz N, Pascanu R, Beattie C, Petersen S, Sadik A, Gaffney S, King H, Kavukcuoglu K, Hassabis D, Hadsell R, Kumaran D. Vector-based navigation using grid-like representations in artificial agents. Nature. 2018 May 9. doi: 10.1038/s41586-018-0102-6. [Epub ahead of print] PubMed PMID: 29743670. 2. Li XF, Liu XM, Huang DR, Cao HJ, Wang JY. PF-06409577 activates AMPK signaling to protect retinal pigment epithelium cells from UV radiation. Biochem Biophys Res Commun. 2018 Jun 18;501(1):293-299. doi: 10.1016/j.bbrc.2018.05.003. Epub 2018 May 8. PubMed PMID: 29733844. 3. Maganha de Almeida AC, Backhaus J, Corso CR. Recycling food waste to clean water: the use of a biodigester's residual liquid inoculum (RLI) to decolourise textile azo dyes. Water Sci Technol. 2018 Jan;77(1-2):398-408. doi: 10.2166/wst.2017.546. PubMed PMID: 29377824; PubMed Central PMCID: wst_2017_546. 4. Takeuchi A, Ogawa Y, Nishinoiri O, Kanno S, Shimizu H. Development of a method for monitoring personal exposure to benzyl violet 4B and direct blue 15 in workplace air. J Occup Health. 2018 Mar 27;60(2):192-195. doi: 10.1539/joh.17-0190-BR. Epub 2017 Dec 19. PubMed PMID: 29269605; PubMed Central PMCID: PMC5886887.

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Direct Violet 1 2586-60-9 微生物学 SARS-CoV Inhibitor pike ACE2 NSC75778 SARS coronavirus Direct Violet1 COVID-19 inhibit CCRIS 2413 NSC-75778 Airedale Violet ND NSC 75778 Direct Violet-1 TNFα TNF-R1 Direct Violet N antiviral inhibitor

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