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Demethoxycurcumin

Catalog No. T6S1683   CAS 22608-11-3
Synonyms: Curcumin II, Desmethoxycurcumin, Monodemethoxycurcumin

1. Demethoxycurcumin (Desmethoxycurcumin) has antioxidant activity. 2. Demethoxycurcumin has anti-inflammatory activity. 3. Demethoxycurcumin has anti-proliferative activity. 4. Demethoxycurcumin has anti-acanthamoebic effect. 5. Demethoxycurcumin is a potential additive natural product in combination with chemotherapeutic agents in drug-resistant cancers. 6. Demethoxycurcumin inhibits energy metabolic and oncogenic signaling pathways through AMPK activation in triple-negative breast cancer cells.

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Demethoxycurcumin Chemical Structure
Demethoxycurcumin, CAS 22608-11-3
Pack Size Availability Price/USD Quantity
20 mg In stock $ 70.00
50 mg In stock $ 160.00
1 mL * 10 mM (in DMSO) In stock $ 50.00
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Purity: 98.1%
Purity: 98%
Purity: 98%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description 1. Demethoxycurcumin (Desmethoxycurcumin) has antioxidant activity. 2. Demethoxycurcumin has anti-inflammatory activity. 3. Demethoxycurcumin has anti-proliferative activity. 4. Demethoxycurcumin has anti-acanthamoebic effect. 5. Demethoxycurcumin is a potential additive natural product in combination with chemotherapeutic agents in drug-resistant cancers. 6. Demethoxycurcumin inhibits energy metabolic and oncogenic signaling pathways through AMPK activation in triple-negative breast cancer cells.
Targets&IC50 BACE1:17 μM
Source
Synonyms Curcumin II, Desmethoxycurcumin, Monodemethoxycurcumin
Molecular Weight 338.35
Formula C20H18O5
CAS No. 22608-11-3

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 50 mg/mL (147.78 mM)

TargetMolReferences and Literature

1. Shieh J M , Chen Y C , Lin Y C , et al. Demethoxycurcumin Inhibits Energy Metabolic and Oncogenic Signaling Pathways through AMPK Activation in Triple-Negative Breast Cancer Cells[J]. Journal of Agricultural and Food Chemistry, 2013, 61(26):6366-6375.

Related compound libraries

This product is contained In the following compound libraries:
Antiparasitic Natural Product Library Anti-Cancer Active Compound Library Anti-Gastroenteritis Natural Product Library Ferroptosis Compound Library Anti-COVID-19 Traditional Chinese Medicine Compound Library Anti-Tumor Natural Product Library Food as Medicine Compound Library Anti-infective Natural Product Library NO PAINS Compound Library Human Metabolite Library

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Keywords

Demethoxycurcumin 22608-11-3 Apoptosis Autophagy Microbiology/Virology oxidation-reduction Antibacterial Antioxidant Bacterial Inhibitor Curcumin II Desmethoxycurcumin inhibit Monodemethoxycurcumin inhibitor

 

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