Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Darunavir Ethanolate (UIC 94017) is an HIV PROTEASE INHIBITOR that is used in the treatment of AIDS and HIV INFECTIONS. Due to the emergence of ANTIVIRAL DRUG RESISTANCE when used alone, it is administered in combination with other ANTI-HIV AGENTS.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | In stock | $ 39.00 | |
10 mg | In stock | $ 55.00 | |
25 mg | In stock | $ 97.00 | |
50 mg | In stock | $ 163.00 | |
100 mg | In stock | $ 263.00 | |
200 mg | In stock | $ 393.00 | |
500 mg | In stock | $ 646.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 51.00 |
Description | Darunavir Ethanolate (UIC 94017) is an HIV PROTEASE INHIBITOR that is used in the treatment of AIDS and HIV INFECTIONS. Due to the emergence of ANTIVIRAL DRUG RESISTANCE when used alone, it is administered in combination with other ANTI-HIV AGENTS. |
Targets&IC50 | HIV-1 protease:1 nM (Ki) |
In vivo | Darunavir effectively combats both wild-type and protease inhibitor (PI)-resistant HIV strains, boasting an oral bioavailability of 37%. Its efficacy is significantly enhanced when used in conjunction with ritonavir, which raises its bioavailability to 82%[3]. |
Synonyms | UIC 94017, Darunavir Ethanolate, TMC114 |
Molecular Weight | 593.74 |
Formula | C29H43N3O8S |
CAS No. | 635728-49-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 93 mg/mL (156.6 mM)
Ethanol: < 1 mg/mL (insoluble or slightly soluble)
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Darunavir Ethanolate 635728-49-3 Microbiology/Virology Proteases/Proteasome HIV Protease inhibit UIC 94017 Darunavir Ethanolate Inhibitor Human immunodeficiency virus HIV TMC-114 TMC114 Darunavir UIC94017 UIC-94017 TMC 114 inhibitor