Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DS-8587 is a DNA topoisomerase inhibitor. DS-8587 exhibits potent antibacterial activity against quinolone-resistant A. baumannii isolates that harbor mutations in quinolone resistance-determining regions. DS-8587 significantly reduces the number of viable bacteria in a murine model of F. necrophorum-induced liver abscess. In the presence of the efflux pump inhibitor 1-(1-napthylmethyl)-piperazine, no significant changes were observed in the MIC for DS-8587.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 10-14 weeks | $ 4,370.00 | |
50 mg | 10-14 weeks | $ 5,780.00 | |
100 mg | 10-14 weeks | $ 8,200.00 |
Description | DS-8587 is a DNA topoisomerase inhibitor. DS-8587 exhibits potent antibacterial activity against quinolone-resistant A. baumannii isolates that harbor mutations in quinolone resistance-determining regions. DS-8587 significantly reduces the number of viable bacteria in a murine model of F. necrophorum-induced liver abscess. In the presence of the efflux pump inhibitor 1-(1-napthylmethyl)-piperazine, no significant changes were observed in the MIC for DS-8587. |
Synonyms | DS 8587, DS8587, DS-8587 free |
Molecular Weight | 493.9 |
Formula | C21H27ClF3N3O5 |
CAS No. | 1356918-39-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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DS-8587 1356918-39-2 DS 8587 DS8587 DS-8587 free inhibitor inhibit