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D-Phenylalanine

Catalog No. T0689 CAS 673-06-3

D-Phenylalanine, a necessary aromatic amino acid, is a precursor of thyroxine, dopamine, melanin, and noradrenaline (norepinephrine).

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D-Phenylalanine, CAS 673-06-3

Pack Size	Availability	Price/USD
50 mg	In stock	$ 30.00
100 mg	In stock	$ 42.00
200 mg	In stock	$ 58.00
1 mL * 10 mM (in H2O)	In stock	$ 48.00

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Purity: 99.77%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	D-Phenylalanine, a necessary aromatic amino acid, is a precursor of thyroxine, dopamine, melanin, and noradrenaline (norepinephrine).
In vitro	Aspirin (oral administration of 200 mg/kg) co-administered with D-phenylalanine (oral administration of 500 mg/kg) rather than with sodium zomepirac (oral administration of 200 mg/kg) resulted in a statistically significant minor increase in the aversion threshold. The oral administration of 500 mg/kg D-Phenylalanine alone caused a minor, statistically insignificant increase in the aversion threshold that was not reversed by naloxone.
In vivo	D-Phenylalanine binds to carboxypeptidase A by disrupting the functional active site at Glu-270 and the hydrogen bonds between zinc-bound water molecules, facilitating the displacement of metal-bound water anions.

Molecular Weight	165.19
Formula	C9H11NO2
CAS No.	673-06-3

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: Insoluble

H2O: 10 mM

References and Literature

1. Christianson DW, et al. J Biol Chem, 1989, 264(22), 12849-12853. 2. Halpern LM, et al. Pain, 1986, 24(2), 223-237.

Citations

1. Chen G Y, Yin S J, Chen L, et al. Nanoporous ZIF-8 Microparticles as Acetylcholinesterase and Alkaline Phosphatase Mimics for the Selective and Sensitive Detection of Ascorbic Acid Oxidase and Copper Ions. Biosensors. 2022, 12(11): 1049.

Related compound libraries

This product is contained In the following compound libraries：

Anti-Cancer Drug Library Drug Repurposing Compound Library EMA Approved Drug Library Anti-Cancer Approved Drug Library Membrane Protein-targeted Compound Library FDA-Approved & Pharmacopeia Drug Library Target-Focused Phenotypic Screening Library Tibetan medicine Compound Library Anti-Obesity Compound Library Natural Product Library for HTS

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Keywords

D-Phenylalanine 673-06-3 Membrane transporter/Ion channel Metabolism Monocarboxylate transporter Endogenous Metabolite Inhibitor inhibit DPhenylalanine D Phenylalanine inhibitor

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