Powder: -20°C for 3 years | In solvent: -80°C for 1 year
CCG-63808 is a reversible inhibitor of regulator of G-protein signaling (RGS) proteins. CCG-63808 dose-dependently inhibits the TR-FRET signal between RGS4-AF488 and Tb-Gαo with IC50 values of 1.9 μM.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 43.00 | |
2 mg | In stock | $ 62.00 | |
5 mg | In stock | $ 97.00 | |
25 mg | In stock | Inquiry | |
50 mg | In stock | Inquiry |
Description | CCG-63808 is a reversible inhibitor of regulator of G-protein signaling (RGS) proteins. CCG-63808 dose-dependently inhibits the TR-FRET signal between RGS4-AF488 and Tb-Gαo with IC50 values of 1.9 μM. |
Targets&IC50 | RGS4:1.9 μM |
In vitro | CCG-63808 showed selectivity among RGS proteins with a potency order of RGS 4 > 19 = 16 > 8 ? 7. CCG-63808 inhibited the GTPase accelerating protein activity of RGS4[1]. |
Molecular Weight | 454.48 |
Formula | C25H15FN4O2S |
CAS No. | 620113-73-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 1 mg/mL (2.20 mM), Sonification is recommended.
You can also refer to dose conversion for different animals. More
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CCG-63808 620113-73-7 GPCR/G Protein GTPase Regulators of G-protein Signaling RGS Protein inhibit Inhibitor Regulator of G-protein Signaling CCG 63808 CCG63808 inhibitor