Powder: -20°C for 3 years
In solvent: -80°C for 2 years
CCG-63808 is a reversible inhibitor of regulator of G-protein signaling (RGS) proteins. CCG-63808 dose-dependently inhibits the TR-FRET signal between RGS4-AF488 and Tb-Gαo with IC50 values of 1.9 μM.
Description | CCG-63808 is a reversible inhibitor of regulator of G-protein signaling (RGS) proteins. CCG-63808 dose-dependently inhibits the TR-FRET signal between RGS4-AF488 and Tb-Gαo with IC50 values of 1.9 μM. |
Targets&IC50 | RGS4:1.9 μM |
In vitro | CCG-63808 showed selectivity among RGS proteins with a potency order of RGS 4 > 19 = 16 > 8 ? 7. CCG-63808 inhibited the GTPase accelerating protein activity of RGS4[1]. |
Molecular Weight | 454.48 |
Formula | C25H15FN4O2S |
CAS No. | 620113-73-7 |
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
DMSO: 1 mg/mL (2.20 mM), Need ultrasonic
( < 1 mg/ml refers to the product slightly soluble or insoluble )
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
CCG-63808 620113-73-7 G蛋白偶联受体 GTPase CCG 63808 Regulators of G-protein Signaling RGS Protein inhibit CCG63808 Inhibitor Regulator of G-protein Signaling inhibitor