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Benoxaprofen

Catalog No. T19679 CAS 51234-28-7

Synonyms: NSC 299582, LY-90459, Benoxaphen. Compound 90459

Benoxaprofen (NSC-299582) is a non-steroidal anti-inflammatory drug.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

Benoxaprofen, CAS 51234-28-7

Pack Size	Availability	Price/USD
1 mg	In stock	$ 213.00
5 mg	In stock	$ 535.00
10 mg	In stock	$ 763.00
25 mg	In stock	$ 1,130.00
50 mg	In stock	$ 1,550.00
100 mg	In stock	$ 1,980.00
1 mL * 10 mM (in DMSO)	In stock	$ 543.00

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Biological Description

Chemical Properties

Storage & Solubility Information

Description

Benoxaprofen (NSC-299582) is a non-steroidal anti-inflammatory drug.

Synonyms	NSC 299582, LY-90459, Benoxaphen. Compound 90459
Molecular Weight	301.72
Formula	C16H12ClNO3
CAS No.	51234-28-7

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 60 mg/ml (198.86 mM)

References and Literature

1. Chin KY, El-Kayat B, Milne A, Hart A. Melanoma diagnosed 27 years after a benoxaprofen-induced photosensitivity reaction. J Dermatol Case Rep. 2012 Mar 27;6(1):5-7. doi: 10.3315/jdcr.2012.1087. PubMed PMID: 22514582; PubMed Central PMCID: PMC3322102. 2. Okada K, Kanoh H, Mohri K. Effects of clofibric acid on the biliary excretion of benoxaprofen glucuronide and taurine conjugate in rats. Pharmazie. 2011 Oct;66(10):777-83. PubMed PMID: 22026160. 3. Dong JQ, Smith PC. Glucuronidation and covalent protein binding of benoxaprofen and flunoxaprofen in sandwich-cultured rat and human hepatocytes. Drug Metab Dispos. 2009 Dec;37(12):2314-22. doi: 10.1124/dmd.109.028944. Epub 2009 Sep 22. PubMed PMID: 19773537; PubMed Central PMCID: PMC2784705. 4. Dong JQ, Liu J, Smith PC. Role of benoxaprofen and flunoxaprofen acyl glucuronides in covalent binding to rat plasma and liver proteins in vivo. Biochem Pharmacol. 2005 Sep 15;70(6):937-48. PubMed PMID: 16046212.

Related compound libraries

This product is contained In the following compound libraries：

Inhibitor Library Bioactive Compound Library Bioactive Compounds Library Max Anti-Cancer Compound Library Mitochondria-Targeted Compound Library Human Metabolite Library Anti-Aging Compound Library ReFRAME Related Library Neuronal Signaling Compound Library Immunology/Inflammation Compound Library

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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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The answer of 19.713 mg appears in the Mass box

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What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Benoxaprofen 51234-28-7 Immunology/Inflammation Neuroscience COX inflammation LRCL-3794 monocyte migration inhibit Cyclooxygenase NSC 299582 LRCL 3794 LY90459 LRCL3794 Inhibitor NSC-299582 lipoxygenase LY-90459 LY 90459 Benoxaphen. Compound 90459 antipyretic compound NSC299582 inhibitor

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