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BRD0418

Catalog No. T30577 CAS 1565827-99-7

Synonyms: BRD 0418, BRD-0418

BRD0418 acts as an upregulator of TRIB1 expression by leading to reprogramming of hepatic lipoprotein metabolism from adipogenesis to clearance it.

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BRD0418, CAS 1565827-99-7

Pack Size	Availability	Price/USD
1 mg	In stock	$ 195.00
5 mg	In stock	$ 447.00
10 mg	In stock	$ 659.00
25 mg	In stock	$ 987.00
50 mg	In stock	$ 1,380.00
1 mL * 10 mM (in DMSO)	In stock	$ 536.00

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Purity: 100%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	BRD0418 acts as an upregulator of TRIB1 expression by leading to reprogramming of hepatic lipoprotein metabolism from adipogenesis to clearance it.
In vitro	Treatment of HepG2 cells with BRD0418 for 6 hours resulted on average in 3.5-fold up-regulation of TRIB1 transcript levels, with half-maximal effect achieved at 2.3 μM concentration of the compound[1].

Synonyms	BRD 0418, BRD-0418
Molecular Weight	488.57
Formula	C29H32N2O5
CAS No.	1565827-99-7

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 55 mg/mL (112.57 mM)

References and Literature

1. Nagiec MM, et al. Modulators of hepatic lipoprotein metabolism identified in a search for small-molecule inducers of tribbles pseudokinase 1 expression. PLoS One. 2015 Mar 26;10(3):e0120295.

Related compound libraries

This product is contained In the following compound libraries：

Kinase Inhibitor Library Bioactive Compound Library Bioactive Compounds Library Max

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

BRD0418 1565827-99-7 Others BRD 0418 BRD-0418 inhibitor inhibit

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