Powder: -20°C for 3 years | In solvent: -80°C for 1 year
BMY-14802 hydrochloride (BMS 181100 hydrochloride) is a selective antagonist of σ receptor (IC50 = 112 nM) with antipsychotic effects. BMY-14802 hydrochloride is an agonist of the α1-adrenergic receptor and 5-HT1A.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 30.00 | |
5 mg | In stock | $ 70.00 | |
10 mg | In stock | $ 113.00 | |
25 mg | In stock | $ 243.00 | |
50 mg | In stock | $ 413.00 | |
100 mg | In stock | $ 618.00 | |
500 mg | In stock | $ 1,330.00 |
Description | BMY-14802 hydrochloride (BMS 181100 hydrochloride) is a selective antagonist of σ receptor (IC50 = 112 nM) with antipsychotic effects. BMY-14802 hydrochloride is an agonist of the α1-adrenergic receptor and 5-HT1A. |
Targets&IC50 | sigma Receptor:112 nM (IC50) |
In vitro | BMY-14802 hydrochloride shows effects on the firing of 5-HTergic and catecholaminergic neurons and affects behaviors in a 5-HT1A-sensitive manner[3]. |
In vivo | Intraperitoneal administration of BMY-14802 hydrochloride (5-20 mg/kg) shows anti-dyskinetic efficacy across a 4-fold dose range against L-DOPA-induced dyskinesias without affecting the efficacy of L-DOPA against lesion-induced akinesia. BMY-14802 hydrochloride reduces D1 and D2 receptor agonist-induced dyskinesias[2]. |
Synonyms | BMS 181100 hydrochloride, BMY-14802-1, BMY 14802 hydrochloride |
Molecular Weight | 384.85 |
Formula | C18H23ClF2N4O |
CAS No. | 105565-55-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: 9.0 mg/mL (23.4 mM), sonification is recommended.
You can also refer to dose conversion for different animals. More
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BMY-14802 hydrochloride 105565-55-7 GPCR/G Protein Neuroscience 5-HT Receptor Sigma receptor Adrenergic Receptor BMS 181100 Hydrochloride BMS-181100 Hydrochloride BMS181100 Hydrochloride BMS 181100 hydrochloride BMY-14802-1 BMY14802 Hydrochloride BMY 14802 hydrochloride BMY 14802 Hydrochloride BMY-14802 Hydrochloride inhibitor inhibit