Shopping Cart
- Remove All
![TargetMol](https://www.targetmol.com/storage/error/oops.webp)
Your shopping cart is currently empty
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $35 | In Stock | |
5 mg | $77 | In Stock | |
10 mg | $129 | In Stock | |
25 mg | $267 | In Stock | |
50 mg | $463 | In Stock | |
100 mg | $787 | In Stock | |
1 mL x 10 mM (in DMSO) | $85 | In Stock |
Description | BI605906 is an IKKβ inhibitor that inhibits tumor necrosis factor alpha-dependent IkappaB degradation and expression of the pro-inflammatory mediator interleukin-6, which can be used to study inflammatory skin diseases such as psoriasis. |
In vitro | BI605906, as a novel IKKβ inhibitor, inhibits TNFα-induced degradation of the NF-κB negative regulator IκB in primary mouse hepatocytes treated with metformin for 3 hours. Additionally, it regulates AMPK and MTOR signaling in a dose-dependent manner[1]. |
Alias | BI-605906, BI 605906 |
Molecular Weight | 432.51 |
Formula | C17H22F2N4O3S2 |
Cas No. | 960293-88-3 |
Storage | store at low temperature|Powder: -20°C for 3 years | In solvent: -80°C for 1 year | ||||||||||||||||||||||||||||||
Solubility Information | DMSO: 40 mg/mL (92.48 mM), Sonication is recommended. | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO
|
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.