Powder: -20°C for 3 years | In solvent: -80°C for 1 year
ARP-100 (MMP-2 Inhibitor III) is a potent and selective matrix metalloproteinase MMP-2 inhibitor (IC50=12 nM). ARP-100 interacts with the S1' pocket of MMP-2 and exhibits anti-invasive properties in an in vitro invasion Matrigel model. ARP-100 has low inhibitory activity against MMP-1 (<50 μM), MMP-3 (4.5 μM), MMP-7 (<50 μM) and MMP-9 (0.2 μM)[1][2].
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 31.00 | |
5 mg | In stock | $ 64.00 | |
10 mg | In stock | $ 98.00 | |
25 mg | In stock | $ 198.00 | |
50 mg | In stock | $ 372.00 | |
100 mg | In stock | $ 597.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 70.00 |
Description | ARP-100 (MMP-2 Inhibitor III) is a potent and selective matrix metalloproteinase MMP-2 inhibitor (IC50=12 nM). ARP-100 interacts with the S1' pocket of MMP-2 and exhibits anti-invasive properties in an in vitro invasion Matrigel model. ARP-100 has low inhibitory activity against MMP-1 (>50 μM), MMP-3 (4.5 μM), MMP-7 (>50 μM) and MMP-9 (0.2 μM)[1][2]. |
Targets&IC50 | MMP1:>50 μM, MMP7:>50 μM, MMP2:12 nM, MMP9:0.2 μM, MMP3:4.5 μM |
In vitro | ARP-100 (50 nM) exhibits a significant reduction in the total number of invasive elongations[1]. |
Synonyms | MMP-2 Inhibitor III |
Molecular Weight | 364.42 |
Formula | C17H20N2O5S |
CAS No. | 704888-90-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 96 mg/mL (263.43 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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ARP-100 704888-90-4 Proteases/Proteasome MMP metalloproteinase Inhibitor Matrix metalloproteinases selective matrigel ARP 100 matrix invasion anti-invasive MMP-2 Inhibitor III ARP100 inhibit inhibitor