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6,8-Diprenylnaringenin

Name: 6,8-Diprenylnaringenin
Brand: TargetMol
SKU: TN3150
Rating: 4.5 (1 reviews)

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Catalog No. TN3150Cas No. 68236-11-3

Alias Senegalensin, Lonchocarpol A

6,8-Diprenylnaringenin (Senegalensin) is a natural product from hop Humulus lupulus. 6,8-Diprenylnaringenin is a breast cancer resistance protein(BCRP) inhibitor with some estrogenicity.

6,8-Diprenylnaringenin

😃Good

Catalog No. TN3150Alias Senegalensin, Lonchocarpol ACas No. 68236-11-3

6,8-Diprenylnaringenin (Senegalensin) is a natural product from hop Humulus lupulus. 6,8-Diprenylnaringenin is a breast cancer resistance protein(BCRP) inhibitor with some estrogenicity.

Pack Size	Price	Availability	Quantity
1 mg	$417	Backorder

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Product Introduction

Bioactivity

Description	6,8-Diprenylnaringenin (Senegalensin) is a natural product from hop Humulus lupulus. 6,8-Diprenylnaringenin is a breast cancer resistance protein(BCRP) inhibitor with some estrogenicity.
In vitro	6,8-Diprenylnaringenin inhibits ABCG2-mediated efflux of Mitoxantrone, and 3H-Methotrexate transport with an IC50 of 0.41 μM in HEK293 cells[1].
Synonyms	Senegalensin, Lonchocarpol A

Chemical Properties

Molecular Weight	408.49
Formula	C₂₅H₂₈O₅
Cas No.	68236-11-3
Smiles	O=C1C=2C(O)=C(C(O)=C(C2OC(C3=CC=C(O)C=C3)C1)CC=C(C)C)CC=C(C)C
Relative Density.	no data available
Color	Yellow
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

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A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

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