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(-)-Coclaurine hydrochloride

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Catalog No. TN1519LCas No. 3422-42-2
Alias (-)-Coclaurine hydrochloride (486-39-5 Free base)

(-)-Coclaurine hydrochloride is an antagonist of nAChRs isolated from Sarcopetalum harveyanum.

(-)-Coclaurine hydrochloride

(-)-Coclaurine hydrochloride

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Purity: 99.07%
Catalog No. TN1519LAlias (-)-Coclaurine hydrochloride (486-39-5 Free base)Cas No. 3422-42-2
(-)-Coclaurine hydrochloride is an antagonist of nAChRs isolated from Sarcopetalum harveyanum.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$117In StockIn Stock
5 mg$262In StockIn Stock
10 mg$388In StockIn Stock
25 mg$592In StockIn Stock
50 mg$828In StockIn Stock
100 mg$1,110In StockIn Stock
200 mg$1,480-In Stock
1 mL x 10 mM (in DMSO)$262In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.07%
Appearance:Solid
Color:White
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Product Introduction

Bioactivity
Description
(-)-Coclaurine hydrochloride is an antagonist of nAChRs isolated from Sarcopetalum harveyanum.
Synonyms(-)-Coclaurine hydrochloride (486-39-5 Free base)
Chemical Properties
Molecular Weight321.8
FormulaC17H20ClNO3
Cas No.3422-42-2
SmilesC([C@H]1C=2C(=CC(OC)=C(O)C2)CCN1)C3=CC=C(O)C=C3.Cl
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 45 mg/mL (139.84 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.1075 mL15.5376 mL31.0752 mL155.3760 mL
5 mM0.6215 mL3.1075 mL6.2150 mL31.0752 mL
10 mM0.3108 mL1.5538 mL3.1075 mL15.5376 mL
20 mM0.1554 mL0.7769 mL1.5538 mL7.7688 mL
50 mM0.0622 mL0.3108 mL0.6215 mL3.1075 mL
100 mM0.0311 mL0.1554 mL0.3108 mL1.5538 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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