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Buntanetap

Name: Buntanetap
Brand: TargetMol
SKU: T17312
Price: 197 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T17312Cas No. 116839-68-0

Alias ANVS401, ANV S401, (+)-Phenserine

Buntanetap ((+)-Phenserine) is an orally active inhibitor of polyneurotoxic proteins (TINAPs) for the study of neurological disorders, endocrine and metabolic disorders, and cardiovascular diseases.

Buntanetap

🥰Excellent

Purity: 98.2%

Catalog No. T17312Alias ANVS401, ANV S401, (+)-PhenserineCas No. 116839-68-0

Buntanetap ((+)-Phenserine) is an orally active inhibitor of polyneurotoxic proteins (TINAPs) for the study of neurological disorders, endocrine and metabolic disorders, and cardiovascular diseases.

Pack Size	Price	Availability
1 mg	$197	In Stock
5 mg	$496	In Stock
10 mg	$793	In Stock
25 mg	$1,480	In Stock
50 mg	$2,150	In Stock
100 mg	$2,800	In Stock
1 mL x 10 mM (in DMSO)	$546	In Stock

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Batch Information

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Purity:98.2%

Resource Download

COA HNMR HPLC

Product Introduction

Bioactivity

Description	Buntanetap ((+)-Phenserine) is an orally active inhibitor of polyneurotoxic proteins (TINAPs) for the study of neurological disorders, endocrine and metabolic disorders, and cardiovascular diseases.
Targets&IC50	AChE:（ki）48 μM, AChE:45.3 μM
In vitro	Buntanetap (1-25 μM, 24 h) significantly decreased the expression of APP, αSYN and HTT in SH-SY5Y cells. [2]
Synonyms	ANVS401, ANV S401, (+)-Phenserine

Chemical Properties

Molecular Weight	337.42
Formula	C₂₀H₂₃N₃O₂
Cas No.	116839-68-0
Smiles	C[C@@]12C=3C(N(C)[C@@]1(N(C)CC2)[H])=CC=C(OC(NC4=CC=CC=C4)=O)C3
Relative Density.	1.228 g/cm3 (Predicted)

Storage & Solubility Information

Storage

keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 200 mg/mL (592.73 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.9637 mL	14.8183 mL	29.6367 mL	148.1833 mL
5 mM	0.5927 mL	2.9637 mL	5.9273 mL	29.6367 mL
10 mM	0.2964 mL	1.4818 mL	2.9637 mL	14.8183 mL
20 mM	0.1482 mL	0.7409 mL	1.4818 mL	7.4092 mL
50 mM	0.0593 mL	0.2964 mL	0.5927 mL	2.9637 mL
100 mM	0.0296 mL	0.1482 mL	0.2964 mL	1.4818 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc