Cat. No. | Product name | CAS No. | Purity | Chemical Structure |
---|---|---|---|---|
T13473L | αvβ1 integrin-IN-1 TFA (1689540-62-2 free base) | T13473L | 98% |
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αvβ1 integrin-IN-1 TFA is an effective and selective αvβ1 integrin inhibitor (IC50: 0.63 nM). | ||||
T78029 | REDV TFA | 98% |
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REDV TFA, the minimal active sequence of the CS5 site in the alternatively spliced type III connecting segment (IIICS) of fibronectin, mediates adhesion to the I... | ||||
T78064 | Synstatin (92-119) | 1259384-47-8 | 98% |
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Synstatin (92-119) serves as an anti-tumor agent by suppressing angiogenesis and cancer cell invasion, chiefly through the down-regulation of integrin αvβ3 and a... | ||||
T78219 | Obtustatin triacetate | 98% |
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Obtustatin triacetate, a 41-residue non-RGD disintegrin isolated from the venom of Vipera lebetina obtusa, serves as a potent and selective inhibitor of the inte... | ||||
T78548 | 3-Hydroxyxanthone | 3722-51-8 | 98% |
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3-Hydroxyxanthone (3-Hydroxy-xanthen-9-one), a xanthone derivative, exhibits inhibitory effects on NADPH-catalyzed lipid peroxidation in human umbilical vein end... | ||||
T78666 | Egaptivon pegol | 934868-74-3 | 98% |
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Egaptivon pegol (ARC1779) is an aptamer that inhibits the interaction of von Willebrand Factor (VWF) with platelet GPIb receptors, exhibiting anti-thrombotic eff... | ||||
T79140 | αvβ6 integrin inhibitor 2 | 313709-47-6 | 98% |
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αvβ6 Integrin Inhibitor 2 is a potent inhibitor of αvβ6 integrin, demonstrating an inhibition concentration (IC50) of 96.5 nM, as detailed in WO2020081154A1, exa... | ||||
T79188 | BT100 | 98% |
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BT100, an aptamer, impedes the interaction of von Willebrand factor (VWF) with platelet glycoprotein GPIb, thus obstructing arterial thrombosis [1]. | ||||
T79792 | αvβ1 integrin-IN-2 | 2234874-68-9 | 98% |
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αvβ1 integrin-IN-2 (compound 32) is a potent inhibitor of ανβ1 and α5β1 integrins, exhibiting IC50 values of 0.9 nM and 33 nM, respectively. Additionally, this c... | ||||
T79918 | α7β1 integrin modulator-1 | 849121-82-0 | 98% |
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α7β1 Integrin Modulator-1 is a potent modulator with research potential for muscular dystrophy [1]. | ||||
T80075 | Cyclo(Ala-Arg-Gly-Asp-Mamb) | 153381-95-4 | 98% |
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Cyclo(Ala-Arg-Gly-Asp-Mamb) is a selective antagonist of the RGD peptide with potential applications in pulmonary arterial hypertension research [1]. | ||||
T80127 | FITC-Ahx-Gly-Arg-Gly-Asp-Ser-Pro | 2022956-44-9 | 98% |
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FITC-Ahx-Gly-Arg-Gly-Asp-Ser-Pro, also known as FITC-linked GRGDSP, is a fluorescent peptide with integrin inhibitory properties. This compound impedes tumor cel... | ||||
T80142 | Cyclo(Gly-Arg-Gly-Asp-Ser-Pro) | 135432-37-0 | 98% |
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Cyclo(Gly-Arg-Gly-Asp-Ser-Pro) (c(GRGDSP)) is an RGD-containing inhibitory peptide and a synthetic α5β1 integrin ligand. It competitively inhibits the binding of... | ||||
T80214 | CRGDfK-thioacetyl ester | 393781-65-2 | 98% |
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cRGDfK-thioacetyl ester, a bioactive polypeptide, exhibits selective affinity for integrins and can modify near-infrared (NIR) fluorescent probes for targeted ca... | ||||
T80529 | VnP-16 | 98% |
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VnP-16 enhances bone formation by stimulating the differentiation and activity of osteoblasts via direct β1 integrin engagement, which subsequently activates FAK... | ||||
T80586 | Anti-Mouse IL-1a Antibody (ALF-161) | 98% |
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Anti-Mouse IL-1a Antibody is an IgG1 subtype inhibitor specific to mouse IL-1a, derived from the Armenian Hamster. | ||||
T81754 | MP6 | 2700321-79-3 | 98% |
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mP6 (Myr-FEEERA-OH), a myristoylated peptide, selectively inhibits Gα 13's interaction with integrin β 3 while preserving talin-dependent integrin function. Addi... | ||||
T9901A-008 | Volociximab | 558480-40-3 | 98% |
Volociximab
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Volociximab (M200) is an IgG4 monoclonal antibody targeting the α5β1 integrin , with antiangiogenic, antitumor and anticancer activity, inhibits the growth of ra... | ||||
T8726 | Cyclo(RGDyK) | 217099-14-4 | 98% |
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Cyclo(RGDyK) is a potent and selective αVβ3 integrin inhibitor with IC50 of 20 nM. | ||||
TP2148 | LXW7 TFA (1313004-77-1 free base) | TP2148 | 98% |
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LXW7 TFA, a cyclic peptide containing Arg-Gly-Asp (RGD), is an integrin αvβ3 inhibitor with an anti-inflammatory effect. LXW7 has a high binding affinity to αvβ3... |