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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T8873 | Bractoppin | Others , DNA/RNA Synthesis | |
Bractoppin is a drug-like inhibitor of phosphopeptide recognition by the human BRCA1 tandem (t)BRCT domain (IC50 = 0.074 μM), which selectively inhibits substrate binding with nanomolar potency in vitro. Structure-activi... | |||
TP2085 | Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH | N-Acetyl-O-phosphono-Tyr-Glu-Glu-Ile-Glu | |
Phosphopeptide ligand for the src SH2 domain (IC50 = 1 μM). Blocks src interactions with EGFR and FAK. | |||
TP2211 | 2B-(SP) | Others | |
Selective phosphopeptide substrate for glycogen synthase kinase-3 (GSK-3) | |||
T40219 | CGP78850 | ||
CGP78850 is a potent and selective Grb2 SH2-phosphopeptide interaction antagonist that holds potential for cancer research. | |||
T38965 | EPQpYEEIPIYL | ||
EPQpYEEIPIYL, a phosphopeptide, is a ligand for the Src homology 2 (SH2) domain. It activates members of the Src family, such as Lck, Hck, and Fyn, through the binding interaction with SH2 domains. | |||
TP2084 | N-Acetyl-O-phosphono-Tyr-Glu Dipentylamide | ||
Phosphopeptide; binds to the src SH2 domain. | |||
T41019 | Histone H1-derived Peptide | Histone H1-derived Peptide | |
Histone H1-derived peptide is a phosphopeptide with peptide substrates that consist of a sequence aligned with the optimal recognition motif for cyclin-dependent kinases (CDKs). | |||
TP2053 | Caffeic acid-pYEEIE | ||
Phosphopeptide ligand for the src SH2 domain (IC50 = 42 nM); displays 30-fold higher affinity than N-acetyl-O-phosphono-Tyr-Glu-Glu-Ile-Glu (Ac-pYEEIE,). | |||
T75929 | Caffeic acid-pYEEIE TFA | ||
Caffeic acid-pYEEIE TFA, a non-phosphopeptide inhibitor, demonstrates strong binding affinity for the GST-Lck-SH2 domain[1]. |