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Search Results for " parasitemia "

9

Compounds

Cat No. Product Name Synonyms Targets
T7532 Piperaquine Parasite
Piperaquine is a bis-quinoline compound that inhibits the ex vivo growth of P. falciparum isolates from malaria-infected patients with IC50s ranging from 11.8-217.3 nM.
T8847 Fosravuconazole L-lysine ethanolate BMS-379224 L-lysine ethanolate,E-1224 L-lysine ethanolate Others , Parasite , Antifungal
Fosravuconazole L-lysine ethanolate (BMS-379224 L-lysine ethanolate) is a broad-spectrum antifungal agent. In Japan, it is approved for the treatment of onychomycosis, a fungal infection of the nail. It is a prodrug that...
T68109 Moxipraquine Antibiotic
Moxipraquine is a novel 8-aminoquinolone compound with anti-infective activity against Trypanosoma cruzi. Moxipraquine effectively inhibited parasitemia but did not eradicate infections in mice or guinea pigs. Moxipraqui...
T68923 FTI-2628
FTI-2628 is a novel inhibitor of protein farnesyltransferase (FT), inhibiting the growth of P. falciparum in red blood cells and suppressing parasitemia.
T63156 SJ000025081
SJ000025081 is a dihydropyridine and can be used as an antimalarial agent. In a mouse malaria model, SJ000025081 significantly inhibited parasitemia in P. yoelii infection.
T78952 Antimalarial agent 26 Parasite
Antimalarial agent 26, a derivative of 1,4-naphthoquinones, demonstrates antimalarial properties through oral administration. It exhibits cytotoxic effects on P. falciparum while maintaining selectivity against mammalian...
T61058 JMI-105
JMI-105 has the potential as an antimalarial agent. JMI-105 is a potent inhibitor of Plasmodium falciparum falcipain-2 protease (PfFP-2) that inhibits the P. falciparum strains CQ S (3D7) and CQ R (RKL-9) growth with IC ...
T35751 Violacein
Violacein is a bacterial metabolite originally isolated from C. violaceum that has antibacterial and antiprotozoal activities.[1] [2] It is produced by C. violaceum as a purple pigment in response to N-hexanoyl homoserin...
T38269 Purfalcamine
Purfalcamine is an orally active, selective Plasmodium falciparum calcium-dependent protein kinase 1 (PfCDPK1) inhibitor with an IC50 of 17 nM and an EC50 of 230 nM. Purfalcamine has antimalarial activity and causes mala...
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