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Piperaquine

Catalog No. T7532 CAS 4085-31-8

Piperaquine is a bis-quinoline compound that inhibits the ex vivo growth of P. falciparum isolates from malaria-infected patients with IC50s ranging from 11.8-217.3 nM.

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Piperaquine, CAS 4085-31-8

Pack Size	Availability	Price/USD
2 mg	6-8 weeks	$ 83.00
5 mg	6-8 weeks	$ 119.00
10 mg	6-8 weeks	$ 171.00
25 mg	6-8 weeks	$ 342.00
50 mg	6-8 weeks	$ 583.00
100 mg	6-8 weeks	$ 873.00

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Piperaquine is a bis-quinoline compound that inhibits the ex vivo growth of P. falciparum isolates from malaria-infected patients with IC50s ranging from 11.8-217.3 nM.
In vivo	Formulations containing piperaquine have been used in combination with artemisinin for the treatment of malaria in HIV-1-positive populations[1]

Molecular Weight	535.52
Formula	C29H32Cl2N6
CAS No.	4085-31-8

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Management of imported malaria in Europe 2. Pyronaridine-artesunate or dihydroartemisinin-piperaquine versus current first-line therapies for repeated treatment of uncomplicated malaria: a randomised, multicentre, open-label, longitudinal, controlled, phase 3b/4 trial.Lancet. 2018 Apr 7;391(10128):1378-1390.

Related Products

Related compounds with same targets

Kuraridine Febrifugine TM2-115 Piperaquine T.cruzi-IN-1 β-Hederin Dehydroemetine Desethyl chloroquine

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Piperaquine 4085-31-8 Microbiology/Virology Parasite ACT inhibit parasitemia therapy antimalarial combination Inhibitor artemisinin drug-based inhibitor

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.